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Protohypericin
🥰Excellent
Catalog No. TN2108Cas No. 548-03-8
Protohypericin, a naphthodianthrone derivative found in the plant Hypericum perforatum, exhibits photocytotoxicity and is utilized in tumor necrosis targeted radiotherapy through its radioiodinated form.
Protohypericin
🥰Excellent
Purity: 98.52%
Catalog No. TN2108Cas No. 548-03-8
Protohypericin, a naphthodianthrone derivative found in the plant Hypericum perforatum, exhibits photocytotoxicity and is utilized in tumor necrosis targeted radiotherapy through its radioiodinated form.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $88 | In Stock | |
| 5 mg | $216 | In Stock | |
| 10 mg | $373 | In Stock | |
| 25 mg | $616 | In Stock | |
| 50 mg | $872 | In Stock | |
| 100 mg | $1,170 | In Stock | |
| 200 mg | $1,580 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $239 | In Stock |
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Purity:98.52%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Protohypericin, a naphthodianthrone derivative found in the plant Hypericum perforatum, exhibits photocytotoxicity and is utilized in tumor necrosis targeted radiotherapy through its radioiodinated form. |
| In vitro | The experimental work was performed in specific filtered light conditions that prevented both an unintended photoconversion of Protohypericin and photosensitization of the cells. Assessing the photocytotoxicity as a function of irradiation time, it was found that the photocytotoxicity of both compounds converged after a long irradiation time (i.e., 15 min), while the difference between the photocytotoxicities was maximal after a short irradiation time (i.e., 1 min)[1] |
| Molecular Weight | 506.46 |
| Formula | C30H18O8 |
| Cas No. | 548-03-8 |
| Smiles | Cc1cc(O)c2c(c1)c1c3c4cc(C)cc(O)c4c(=O)c4c(O)cc(O)c(c5c(O)cc(O)c(c15)c2=O)c34 |
| Relative Density. | 1.736g/cm3 |
| Color | Black |
| Appearance | Solid |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: Slightly soluble  |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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