Shopping Cart

Remove All
Your shopping cart is currently empty

Imatinib impurities3

Name: Imatinib impurities3
Brand: TargetMol
SKU: T67847
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T67847Cas No. 404844-11-7

Imatinib impurities3 is a protein kinases inhibitor with IC50 values of 6.95uM, 0.245uM, 0.139uM for ABL1 wt, KIT wt, PDGFRR wt, respectively.

Imatinib impurities3

🥰Excellent

Purity: 98.63%

Catalog No. T67847Cas No. 404844-11-7

Imatinib impurities3 is a protein kinases inhibitor with IC50 values of 6.95uM, 0.245uM, 0.139uM for ABL1 wt, KIT wt, PDGFRR wt, respectively.

Pack Size	Price	Availability
10 mg	$36	In Stock
25 mg	$64	In Stock
50 mg	$94	In Stock
100 mg	$137	In Stock
200 mg	$197	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98.63%

Resource Download

COA HNMR LCMS LCMS HPLC

Product Introduction

Bioactivity

Description	Imatinib impurities3 is a protein kinases inhibitor with IC50 values of 6.95uM, 0.245uM, 0.139uM for ABL1 wt, KIT wt, PDGFRR wt, respectively.
Targets&IC50	Abl-1 (WT):6.95μM, PDGFR:1.39 μM, c-Kit (WT):0.245 μM

Chemical Properties

Molecular Weight	429.9
Formula	C₂₄H₂₀ClN₅O
Cas No.	404844-11-7
Smiles	Cc1ccc(NC(=O)c2ccc(CCl)cc2)cc1Nc1nccc(n1)-c1cccnc1

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (127.94 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3261 mL	11.6306 mL	23.2612 mL	116.3061 mL
5 mM	0.4652 mL	2.3261 mL	4.6522 mL	23.2612 mL
10 mM	0.2326 mL	1.1631 mL	2.3261 mL	11.6306 mL
20 mM	0.1163 mL	0.5815 mL	1.1631 mL	5.8153 mL
50 mM	0.0465 mL	0.2326 mL	0.4652 mL	2.3261 mL
100 mM	0.0233 mL	0.1163 mL	0.2326 mL	1.1631 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc