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Perospirone hydrochloride

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Catalog No. T8136Cas No. 129273-38-7
Alias SM-9018 hydrochloride, Perospirone HCl

Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist.

Perospirone hydrochloride
Other Forms of Perospirone hydrochloride:

Perospirone hydrochloride

🥰Excellent
Purity: 99.37%
Catalog No. T8136Alias SM-9018 hydrochloride, Perospirone HClCas No. 129273-38-7
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$38In StockIn Stock
50 mg$56In StockIn Stock
100 mg$82In StockIn Stock
200 mg$118-In Stock
1 mL x 10 mM (in DMSO)$30In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.37%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist.
Targets&IC50
D1 receptor:41 nM (Ki), 5-HT1A receptor:2.9 nM (Ki), D2 receptor:1.4 nM (Ki), 5-HT2A receptor:0.6 nM (Ki), 5-HT1 receptor:18 nM (Ki)
SynonymsSM-9018 hydrochloride, Perospirone HCl
Chemical Properties
Molecular Weight463
FormulaC23H31ClN4O2S
Cas No.129273-38-7
SmilesCl.O=C1C2CCCCC2C(=O)N1CCCCN1CCN(c2nsc3ccccc23)CC1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 92 mg/mL (198.7 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1598 mL10.7991 mL21.5983 mL107.9914 mL
5 mM0.4320 mL2.1598 mL4.3197 mL21.5983 mL
10 mM0.2160 mL1.0799 mL2.1598 mL10.7991 mL
20 mM0.1080 mL0.5400 mL1.0799 mL5.3996 mL
50 mM0.0432 mL0.2160 mL0.4320 mL2.1598 mL
100 mM0.0216 mL0.1080 mL0.2160 mL1.0799 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

SM-9018 HydrochlorideSM9018 HydrochlorideSM-9018SM9018SM 9018 HydrochlorideSM 9018Serotonin ReceptorschizophrenicPerospirone hydrochloridePerospirone HydrochloridePerospironeOrallyInhibitorinhibitDopamineReceptorDopamine ReceptorDopaminediseaseD2-receptorcognitiveatypicalantipsychotic5-hydroxytryptamine Receptor5HTReceptor5-HT2A5-HT1A5-HT Receptor5HT Receptor5-HT
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