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Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681)
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Catalog No. TMAC-03015
Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) is a Mouse antibody targeting Phospho-p70 S6 Kinase (Ser 411). Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) can be used in WB,IP,IF,IHC-P.
Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681)
Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681)
😃Good
Catalog No. TMAC-03015
Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) is a Mouse antibody targeting Phospho-p70 S6 Kinase (Ser 411). Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) can be used in WB,IP,IF,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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| Description | Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) is a Mouse antibody targeting Phospho-p70 S6 Kinase (Ser 411). Anti-Phospho-p70 S6 Kinase (Ser 411) Antibody (7V681) can be used in WB,IP,IF,IHC-P. |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | In studies to elucidate key regulatory pathways in signal transduction, several protein serine/threonine (Ser/Thr) kinases have been identified. Included among such kinases are two distinct families of 40S ribosomal protein S6 Ser/Thr kinases present in somatic animal cells, designated p70 S6 kinase and p90 Rsk kinase. p90 Rsk kinase is maximally activated within minutes of addition of growth factors or phorbol ester to cultured cells followed by activation of p70 S6 kinase. Both enzymes are regulated by serine/threonine phosphorylation, suggesting that specific kinases may exist upstream in the signaling pathway that regulate these kinases. In fact, evidence suggests that one such family of activating enzymes includes the members of the ERK MAP kinase family. The ERK MAP kinases are, in turn, regulated by phosphorylation at threonine and tyrosine residues by a protein kinase designated MEK. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A sequence containing Ser 411 phosphorylated p70 S6 kinase α isoform 2 of human origin |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 70 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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