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Mosapride

Name: Mosapride
Brand: TargetMol
SKU: T8128
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T8128Cas No. 112885-41-3

Alias TAK-370, AS-4370

Mosapride (AS-4370) is a selective 5HT4 agonist

Mosapride

🥰Excellent

Purity: 99.56%

Catalog No. T8128Alias TAK-370, AS-4370Cas No. 112885-41-3

Mosapride (AS-4370) is a selective 5HT4 agonist

Pack Size	Price	Availability
10 mg	$44	In Stock
25 mg	$71	In Stock
50 mg	$101	In Stock
100 mg	$147	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock

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Batch Information

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Purity:99.56%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Mosapride (AS-4370) is a selective 5HT4 agonist
Synonyms	TAK-370, AS-4370

Chemical Properties

Molecular Weight	421.89
Formula	C₂₁H₂₅ClFN₃O₃
Cas No.	112885-41-3
Smiles	C(NCC1CN(CC2=CC=C(F)C=C2)CCO1)(=O)C3=C(OCC)C=C(N)C(Cl)=C3
Relative Density.	1.272 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 84 mg/mL (199.1 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3703 mL	11.8514 mL	23.7029 mL	118.5143 mL
5 mM	0.4741 mL	2.3703 mL	4.7406 mL	23.7029 mL
10 mM	0.2370 mL	1.1851 mL	2.3703 mL	11.8514 mL
20 mM	0.1185 mL	0.5926 mL	1.1851 mL	5.9257 mL
50 mM	0.0474 mL	0.2370 mL	0.4741 mL	2.3703 mL
100 mM	0.0237 mL	0.1185 mL	0.2370 mL	1.1851 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc