IL-1F8 Protein, Human, Recombinant

Name: IL-1F8 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-02458
Rating: 4.5 (1 reviews)

(Synonyms: interleukin 36, β, interleukin 36, beta, IL36B, IL-1H2, IL1H2, IL-1F8, IL1F8, IL1-ETA, FILI-(ETA), FIL1H, FIL1-(ETA), FIL1) Copy Product Info

Synonyms: interleukin 36, β, interleukin 36, beta, IL36B, IL-1H2, IL1H2, IL-1F8, IL1F8, IL1-ETA, FILI-(ETA), FIL1H, FIL1-(ETA), FIL1

Catalog No. TMPY-02458 Copy Product Info

IL-1F8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.23 kDa and the accession number is Q9NZH7-2.

Pack Size	Price	USA Stock	Global Stock
5 µg	$87	7-10 days	7-10 days
10 µg	$142	7-10 days	7-10 days
20 µg	$233	7-10 days	7-10 days
50 µg	$535	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	IL-1F8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.23 kDa and the accession number is Q9NZH7-2.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	Q9NZH7-2
Construction	Arg5-Glu157
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS, 8% trehalose, 0.02% Tween-20 (pH 7.4).
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	interleukin 36, β, interleukin 36, beta, IL36B, IL-1H2, IL1H2, IL-1F8, IL1F8, IL1-ETA, FILI-(ETA), FIL1H, FIL1-(ETA), FIL1
Research Background	Interleukin-1 family member 8(IL1F8) also known as IL36B, is a member of the interleukin 1(IL-1) cytokine family. IL1F8 may contain a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines includes four members, with three having pro-inflammatory effects such as IL1F8 and the fourth member being an IL-1 receptor antagonist (IL-1Ra). IL-1 family members exert their effects through binding to receptors that belong to the IL-1 receptor (IL-1R) family. IL1F8 exerts proinflammatory effects in primary human joint cells. Joint and serum IL-1F8 protein levels did not correlate with inflammation, but they were high in some human serum samples tested, including samples from patients with rheumatoid arthritis. IL1F8 also activated NK-κB.

Chemical Properties

Molecular Weight

17.23 kDa (predicted); 18 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.