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N6-(2-Phenylethyl)adenosine

Name: N6-(2-Phenylethyl)adenosine
Brand: TargetMol
SKU: T12163
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12163Cas No. 20125-39-7

Alias N6-Phenylethyladenosine, N6-Phenethyladenosine

N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and adenosine receptor agonist with Ki values of 11.8 nM for rat A1 receptors and 30.1 nM for human A1 receptors.

N6-(2-Phenylethyl)adenosine

🥰Excellent

Purity: 99.83%

Catalog No. T12163Alias N6-Phenylethyladenosine, N6-PhenethyladenosineCas No. 20125-39-7

N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and adenosine receptor agonist with Ki values of 11.8 nM for rat A1 receptors and 30.1 nM for human A1 receptors.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$29	In Stock	In Stock
25 mg	$57	In Stock	In Stock
50 mg	$112	In Stock	In Stock
100 mg	$196	In Stock	In Stock
200 mg	$352	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.83%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and adenosine receptor agonist with Ki values of 11.8 nM for rat A1 receptors and 30.1 nM for human A1 receptors.
Targets&IC50	A1AR (human):30.1 nM (ki), A3AR (human):0.63 nM (ki), A1AR (rat):ki:11.8 nM
In vitro	The Ki value of human A3 is 0.63 nM. In CHO cells, N6-(2-Phenylethyl)adenosine inhibits A2 with IC50s of 560 nM and 2250 nM for rat and human[1].
Synonyms	N6-Phenylethyladenosine, N6-Phenethyladenosine

Chemical Properties

Molecular Weight	371.39
Formula	C₁₈H₂₁N₅O₄
Cas No.	20125-39-7
Smiles	OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCCc3ccccc3)ncnc12
Relative Density.	1.57 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 0.1 mg/mL (insoluble)

DMSO: 95 mg/mL (255.80 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (8.89 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6926 mL	13.4629 mL	26.9259 mL	134.6294 mL
5 mM	0.5385 mL	2.6926 mL	5.3852 mL	26.9259 mL
10 mM	0.2693 mL	1.3463 mL	2.6926 mL	13.4629 mL
20 mM	0.1346 mL	0.6731 mL	1.3463 mL	6.7315 mL
50 mM	0.0539 mL	0.2693 mL	0.5385 mL	2.6926 mL
100 mM	0.0269 mL	0.1346 mL	0.2693 mL	1.3463 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc