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Anti-CD8 alpha Polyclonal Antibody 3 (Synonyms: p32, OKT8 T-cell antigen, MAL, Lyt-2, Leu2, CD8a molecule||...)
Catalog No. TMAB-00390 Copy Product Info
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Anti-CD8 alpha Polyclonal Antibody 3 is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Polyclonal Antibody 3 can be used in WB.
Anti-CD8 alpha Polyclonal Antibody 3
Copy Product Info🥰Excellent
Catalog No. TMAB-00390
Synonyms p32, OKT8 T-cell antigen, MAL, Lyt-2, Leu2, CD8a molecule, CD8a, CD8 α/CD8A, CD8
Anti-CD8 alpha Polyclonal Antibody 3 is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Polyclonal Antibody 3 can be used in WB.
Anti-CD8 alpha Polyclonal Antibody 3
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CD8 alpha Polyclonal Antibody 3 is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Polyclonal Antibody 3 can be used in WB. |
| Synonyms | p32, OKT8 T-cell antigen, MAL, Lyt-2, Leu2, CD8a molecule, CD8a, CD8 α/CD8A, CD8 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat |
| Verified Activity | 25 μg total protein per Lane of various lysates probed with CD8 polyclonal antibody, unconjugated (TMAB-00390) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] |
| Immunogen | KLH conjugated synthetic peptide: rat CD8 |
| Antigen Species | Rat |
| Gene Name | CD8A |
| Protein Name | T-cell surface glycoprotein CD8 alpha chain |
| Biology Area | Cytotoxic Cells,CD,CD markers |
| Function | Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. |
| Molecular Weight | Theoretical: 27 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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