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Anti-CX3CL1/Fractalkine Antibody-HRP (8F783) is a HRP-conjugated Rabbit antibody targeting CX3CL1/Fractalkine. Anti-CX3CL1/Fractalkine Antibody-HRP (8F783) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $409 | 7-10 days |
Description | Anti-CX3CL1/Fractalkine Antibody-HRP (8F783) is a HRP-conjugated Rabbit antibody targeting CX3CL1/Fractalkine. Anti-CX3CL1/Fractalkine Antibody-HRP (8F783) can be used in ELISA. |
Alias | chemokine (C-X3-C motif) ligand 1 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 8F783 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 0.1-1 μg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Fractalkine / CX3CL1 (rh Fractalkine / CX3CL1; TMPY-00737; NP_002987.1; Met 1-Arg 339), and conjugated with horseradish-peroxidase (HRP). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine / CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines. |
Conjucates | HRP |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | Recombinant Human Fractalkine / CX3CL1 protein (TMPY-00737) |
Antigen Species | Human |
Biology Area | Neuroinflammation |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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