Clusterin Protein, Mouse, Recombinant (His)

Name: Clusterin Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-01694
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Sugp-2, SP-40, Sgp-2, Sgp2, D14Ucla3, clusterin, Cli, ApoJ, AI893575) Copy Product Info

Synonyms: Sugp-2, SP-40, Sgp-2, Sgp2, D14Ucla3, clusterin, Cli, ApoJ, AI893575

Catalog No. TMPY-01694 Copy Product Info

Clusterin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is Q06890.

Pack Size	Price	USA Stock	Global Stock
5 µg	$42	-	In Stock
10 µg	$65	-	In Stock
20 µg	$98	-	In Stock
50 µg	$197	-	In Stock
100 µg	$329	7-10 days	7-10 days
200 µg	$583	7-10 days	7-10 days
500 µg	$1,230	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:94.8%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Clusterin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is Q06890.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q06890
Construction	A DNA sequence encoding the mouse CLU (NP_038520.2) (Met 1-Glu 448) was expressed, with a C-terminal polyhistidine tag. Predicted N terminal: Glu 22 (β chain) & Ser 227(α chain)
Protein Purity	> 96 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	Sugp-2, SP-40, Sgp-2, Sgp2, D14Ucla3, clusterin, Cli, ApoJ, AI893575
Research Background	Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.

Chemical Properties

Molecular Weight

50.8 kDa (predicted); 32, 42 and 65 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.