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N-acetyldopamine

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Catalog No. T40158Cas No. 2494-12-4
Alias NADA

N-Acetyldopamine is a natural catecholamine exhibiting immunomodulatory and antioxidant effects, capable of attenuating LPS-induced TNF-α and superoxide production in THP-1 cells. It inhibits sepiapterin reductase activity.

N-acetyldopamine
Other Forms of N-acetyldopamine:
N-ArachidonyldopamineT62530199875-69-9
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N-acetyldopamine

🥰Excellent
Catalog No. T40158Alias NADACas No. 2494-12-4
N-Acetyldopamine is a natural catecholamine exhibiting immunomodulatory and antioxidant effects, capable of attenuating LPS-induced TNF-α and superoxide production in THP-1 cells. It inhibits sepiapterin reductase activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mgInquiry-In Stock
100 mg$75-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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COA HNMR

Product Introduction

Bioactivity
Description
N-Acetyldopamine is a natural catecholamine exhibiting immunomodulatory and antioxidant effects, capable of attenuating LPS-induced TNF-α and superoxide production in THP-1 cells. It inhibits sepiapterin reductase activity.
In vitro
N-acetyldopamine (0–400 μM) treatment of THP-1 cells for 24 hours exhibited a dose-dependent, significant inhibitory effect on LPS-stimulated TNF-α production [1].
N-acetyldopamine (0–400 μM) pretreatment of HL-60-derived neutrophils for 30 minutes moderately reduced PMA- and fMLP-stimulated superoxide generation in a dose-dependent manner [1].
SynonymsNADA
Chemical Properties
Molecular Weight195.22
FormulaC10H13NO3
Cas No.2494-12-4
Relative Density.1.235 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (409.79 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.1224 mL25.6121 mL51.2243 mL256.1213 mL
5 mM1.0245 mL5.1224 mL10.2449 mL51.2243 mL
10 mM0.5122 mL2.5612 mL5.1224 mL25.6121 mL
20 mM0.2561 mL1.2806 mL2.5612 mL12.8061 mL
50 mM0.1024 mL0.5122 mL1.0245 mL5.1224 mL
100 mM0.0512 mL0.2561 mL0.5122 mL2.5612 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

N-acetyldopamineNacetyldopamineN acetyldopamine
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