Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody
😃Good
Catalog No. TMAC-00428
Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CTNNB1 (Ser715). Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody can be used in WB,IHC.
Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody
Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody
😃Good
Catalog No. TMAC-00428
Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CTNNB1 (Ser715). Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody can be used in WB,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CTNNB1 (Ser715). Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody can be used in WB,IHC. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-100 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 715 (D-P-S(p)-Y-R) derived from Human beta-catenin |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 92 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody | purchase Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody | Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody cost | order Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody | Anti-Phospho-CTNNB1 (Ser715) Polyclonal Antibody molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.