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Anti-CD86 Antibody-APC (5D537) (Synonyms: LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2)

Name: Anti-CD86 Antibody-APC (5D537)
Brand: TargetMol
SKU: TMAY-03702A
Rating: 4.5 (1 reviews)

Catalog No. TMAY-03702A Copy Product Info

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Anti-CD86 Antibody-APC (5D537) is a APC-conjugated Mouse antibody targeting CD86. Anti-CD86 Antibody-APC (5D537) can be used in FCM.

Anti-CD86 Antibody-APC (5D537)

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Catalog No. TMAY-03702A

Synonyms LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2

Anti-CD86 Antibody-APC (5D537) is a APC-conjugated Mouse antibody targeting CD86. Anti-CD86 Antibody-APC (5D537) can be used in FCM.

Anti-CD86 Antibody-APC
(5D537)

Pack Size	Price	USA Stock	Global Stock	Quantity
25 T	$34	7-10 days	7-10 days
100 T	$104	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Description	Anti-CD86 Antibody-APC (5D537) is a APC-conjugated Mouse antibody targeting CD86. Anti-CD86 Antibody-APC (5D537) can be used in FCM.
Synonyms	LAB72, CD86 antigen, CD28LG2, B7-2, B70, B7.2
Ig Type	Mouse IgG2b
Clone	5D537
Reactivity	Rat
Specificity	Rat B7-2/CD86
Verified Activity	Flow cytometric analysis of rat CD86 expression on LPS-stimulated SD rat splenocytes. Cells were stained with APC-conjugated anti-rat CD86. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application	FCM
Recommended Dose	10 μl/Test, 0.1 mg/ml
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD86 (rR CD86; TMPY-02016; NP_064466.1; Met1-Ile250) and conjugated with APC under optimum conditions, the unreacted APC was removed.
Purification	Protein A
Appearance	Liquid
Formulation	PBS solution containing 0.5% BSA and 0.03%ProClin300
Research Background	CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy

Related Conjugates and Formulations

Conjucates	APC
Others Formats	Unconjugated/FITC/HRP/PE
Antibody Types Available	5

Antigen Details

Immunogen	Recombinant Protein: Rat CD86 Protein (TMPY-02016)
Antigen Species	Rat
Biology Area	Cancer Drug Targets

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
Transport	Shipping with blue ice.

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Keywords

LAB-72LAB 72B-70B 70

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