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DSPE-PEG5000-Mal ammonium
🥰Excellent
Catalog No. T84748Cas No. 474922-22-0
Alias DSPE-PEG5000 Maleimide ammonium, 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium
DSPE-PEG5000-Mal ammonium is an amphiphilic conjugate composed of DSPE phospholipid and a maleimide functional group, commonly utilized in the preparation of nanostructured lipid carriers for drug delivery applications. DSPE-PEG5000-Mal ammonium enhances both systemic circulation time and colloidal stability of encapsulated therapeutic agents, and its variant DSPE-PEG5000-Mal incorporates a PEG5000 chain to further improve pharmacokinetic properties and biocompatibility in nanomedicine formulations.
DSPE-PEG5000-Mal ammonium
DSPE-PEG5000-Mal ammonium
🥰Excellent
Catalog No. T84748Alias DSPE-PEG5000 Maleimide ammonium, 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammoniumCas No. 474922-22-0
DSPE-PEG5000-Mal ammonium is an amphiphilic conjugate composed of DSPE phospholipid and a maleimide functional group, commonly utilized in the preparation of nanostructured lipid carriers for drug delivery applications. DSPE-PEG5000-Mal ammonium enhances both systemic circulation time and colloidal stability of encapsulated therapeutic agents, and its variant DSPE-PEG5000-Mal incorporates a PEG5000 chain to further improve pharmacokinetic properties and biocompatibility in nanomedicine formulations.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $30 | - | In Stock | |
| 10 mg | $40 | - | In Stock | |
| 25 mg | $77 | - | In Stock | |
| 50 mg | $123 | - | In Stock | |
| 100 mg | $189 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | DSPE-PEG5000-Mal ammonium is an amphiphilic conjugate composed of DSPE phospholipid and a maleimide functional group, commonly utilized in the preparation of nanostructured lipid carriers for drug delivery applications. DSPE-PEG5000-Mal ammonium enhances both systemic circulation time and colloidal stability of encapsulated therapeutic agents, and its variant DSPE-PEG5000-Mal incorporates a PEG5000 chain to further improve pharmacokinetic properties and biocompatibility in nanomedicine formulations. |
| In vitro | Immunoliposomes prepared based on DSPE-PEG5000-Mal ammonium can be used for brain-targeted drug delivery [2]. |
| Synonyms | DSPE-PEG5000 Maleimide ammonium, 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium |
| Molecular Weight | 2000(Average) |
| Formula | (C2H4O)nC51H92N1O13P.H3N |
| Cas No. | 474922-22-0 |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | DMF: 8 mg/mL, Sonication is recommended. Ethanol: 16 mg/mL, Sonication is recommended. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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