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IL-16 Protein, Human, Recombinant

(Synonyms: Pro-Interleukin-16, Lymphocyte Chemoattractant Factor, LCF, Interleukin-16, IL-16, IL16) Copy Product Info

Synonyms: Pro-Interleukin-16, Lymphocyte Chemoattractant Factor, LCF, Interleukin-16, IL-16, IL16

Catalog No. TMPJ-00451 Copy Product Info
Purity: 97.71%
Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$1127-10 days7-10 days
10 μg$1837-10 days7-10 days
20 μg$2927-10 days7-10 days
50 μg$5457-10 days7-10 days
100 μg$8387-10 days7-10 days
200 μg$1,2907-10 days7-10 days
500 μg$2,2907-10 days7-10 days
1 mg$3,2707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:97.71%
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberAAC12732.1
Amino AcidMet1-Ser130
ConstructionMet1-Ser130
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
IL-16 Protein, Human, RecombinantIL-16 Protein, Human, Recombinant
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.0.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsPro-Interleukin-16, Lymphocyte Chemoattractant Factor, LCF, Interleukin-16, IL-16, IL16
Research Background
Chemical Properties
Molecular Weight16-20 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: IL-16 Protein, Human, Recombinant chemical structure | IL-16 Protein, Human, Recombinant molecular weight