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5-trans Latanoprost

Catalog No. T37213 CAS 913258-34-1

Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been changed from cis (Z) to trans (E). The trans isomer of latanoprost occurs as an impurity of between 2-5% in most commercial preparations of the bulk drug product. The present compound was prepared primarily as an analytical standard for detection and quantitation of this impurity. From what can be inferred from the study of other trans isomers of F-type prostaglandins, 5-trans latanoprost's biological activity is likely to be similar to that of the cis isomer. However, there are no specific published reports on the biological activity, and on the intraocular hypotensive activity in particular, of 5-trans latanoprost.

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5-trans Latanoprost, CAS 913258-34-1

Pack Size	Availability	Price/USD
1 mg	35 days	$ 183.00
5 mg	35 days	$ 793.00
10 mg	35 days	$ 1,430.00
50 mg	35 days	$ 4,470.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	432.601
Formula	C26H40O5
CAS No.	913258-34-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL

DMF: 100 mg/mL

Ethanol: Miscible

PBS (pH 7.2): 1.5 mg/mL

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

5-trans Latanoprost 913258-34-1 5 trans Latanoprost 5trans Latanoprost inhibitor inhibit

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