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EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated
(Synonyms: Membrane glycoprotein gp42, HT7 antigen, CD147, Bsg, Basigin, Basic immunoglobulin superfamily) Copy Product InfoSynonyms: Membrane glycoprotein gp42, HT7 antigen, CD147, Bsg, Basigin, Basic immunoglobulin superfamily
Catalog No. TMPJ-00159 Copy Product Info
Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $129 | 7-10 days | 7-10 days | |
| 10 μg | $213 | 7-10 days | 7-10 days | |
| 20 μg | $355 | 7-10 days | 7-10 days | |
| 50 μg | $625 | 7-10 days | 7-10 days | |
| 100 μg | $963 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-Avi-6xHis |
| Accession Number | P35613-2 |
| Amino Acid | Ala22-His205 |
| Construction | Ala22-His205 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Membrane glycoprotein gp42, HT7 antigen, CD147, Bsg, Basigin, Basic immunoglobulin superfamily |
| Research Background |
| Molecular Weight | 30-45 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated chemical structure | EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated molecular weight
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