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Clorprenaline hydrochloride

Name: Clorprenaline hydrochloride
Brand: TargetMol
SKU: T0248
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0248Cas No. 6933-90-0

Alias NSC 334693, Clorprenaline HCl

Clorprenaline hydrochloride (Clorprenaline HCl) is a beta-2 adrenergic agonist with bronchodilator activity.

Clorprenaline hydrochloride

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Purity: 99.59%

Catalog No. T0248Alias NSC 334693, Clorprenaline HClCas No. 6933-90-0

Clorprenaline hydrochloride (Clorprenaline HCl) is a beta-2 adrenergic agonist with bronchodilator activity.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$33	In Stock	In Stock
50 mg	$47	In Stock	In Stock
100 mg	$68	In Stock	In Stock
200 mg	$97	-	In Stock
500 mg	$159	-	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.59%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Clorprenaline hydrochloride (Clorprenaline HCl) is a beta-2 adrenergic agonist with bronchodilator activity.
In vitro	The linear ranges 8.0-1.6 ×103 ng/mL for Clorprenaline in a single chromatographic run, the detection limits 3.0 ng/mL for Clorprenaline. [1] Clorprenaline is a bronchodilator that has been separated by CE based on affinity-interaction or with charged CD-CZE sulfobuthylether (SBE)-β-CD or β-CD-phosphate with resolution greater than 1.2. Clorprenaline is separated in optimum condition of 60 mM HP-β-CD. [2] Clorprenaline hydrochloride (a), bromhexine hydrochloride (b) and decloxizine hydrochloride (c) are three main components in clorprenaline compound tablet. [3]
In vivo	In a single chromatographic run, the linear range of clorprenaline was 8.0-1.6 × 103 ng/mL, with a limit of detection of 3.0 ng/mL.[1] Clorprenaline is a bronchodilator that has been separated by affinity-interaction-based CE or charged CD-CZE sulfobutyl ether (SBE)-β-CD or β-CD -phosphates at a resolution greater than 1.2. Clorprenaline was separated under optimal conditions at 60 mM HP-β-CD. [2] Clorprenaline hydrochloride, bromhexine hydrochloride, and deslorohydroxyzine hydrochloride are the three main ingredients of Clorprenaline compound tablets. [3]
Synonyms	NSC 334693, Clorprenaline HCl

Chemical Properties

Molecular Weight	250.16
Formula	C₁₁H₁₇Cl₂NO
Cas No.	6933-90-0
Smiles	Cl.CC(C)NCC(O)c1ccccc1Cl
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 47 mg/mL (187.88 mM), Sonication is recommended.

H2O: 46 mg/mL (183.88 mM), Sonication is recommended.

DMSO: 55 mg/mL (219.86 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.99 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9974 mL	19.9872 mL	39.9744 mL	199.8721 mL
5 mM	0.7995 mL	3.9974 mL	7.9949 mL	39.9744 mL
10 mM	0.3997 mL	1.9987 mL	3.9974 mL	19.9872 mL
20 mM	0.1999 mL	0.9994 mL	1.9987 mL	9.9936 mL
50 mM	0.0799 mL	0.3997 mL	0.7995 mL	3.9974 mL
100 mM	0.0400 mL	0.1999 mL	0.3997 mL	1.9987 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc