Mal-PEG5-C2-NH2 hydrochloride

Name: Mal-PEG5-C2-NH2 hydrochloride
Brand: TargetMol
SKU: T40118
Rating: 4.5 (1 reviews)

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Catalog No. T40118Cas No. 2454216-21-6

Alias Mal-PEG5-C2-NH2 hydrochloride

Mal-PEG5-C2-NH2 hydrochloride is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).

Mal-PEG5-C2-NH2 hydrochloride

😃Good

Catalog No. T40118Alias Mal-PEG5-C2-NH2 hydrochlorideCas No. 2454216-21-6

Mal-PEG5-C2-NH2 hydrochloride is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Mal-PEG5-C2-NH2 hydrochloride is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).
In vitro	PROTACs comprise two ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets the desired protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs facilitate the selective degradation of target proteins[1].
Synonyms	Mal-PEG5-C2-NH2 hydrochloride

Chemical Properties

Molecular Weight	396.87
Formula	C₁₆H₂₉ClN₂O₇
Cas No.	2454216-21-6
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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