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Mp1 Protein, Human, Recombinant (His)

Catalog No. TMPJ-01378
Synonyms: Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1, LAMTOR3, Mp1, Ragulator Complex Protein LAMTOR3, Mitogen-Activated Protein Kinase Scaffold Protein 1, Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3, MEK-Binding Partner 1, M

Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.

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Mp1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.
Species Human
Expression System E. coli
Tag N-6His
Accession Number Q9UHA4
Synonyms Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1, LAMTOR3, Mp1, Ragulator Complex Protein LAMTOR3, Mitogen-Activated Protein Kinase Scaffold Protein 1, Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3, MEK-Binding Partner 1, M
Amino Acid Met1-Ser124
Construction Recombinant Human Mitogen-Activated Protein Kinase Scaffold Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Ser124 is expressed with a 6His tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 15 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 5mM DTT, 30% Glycerol, pH 8.0.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.

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Keywords

Mp1 Protein, Human, Recombinant (His) Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1 LAMTOR3 LAMTOR-3 Mp1 Ragulator Complex Protein LAMTOR3 Mitogen-Activated Protein Kinase Scaffold Protein 1 Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3 MEK-Binding Partner 1 M LAMTOR 3 recombinant recombinant-proteins proteins protein

 

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