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IL-17RC Protein, Human, Recombinant(aa 1-454, hFc)
(Synonyms: UNQ6118/PRO20040/PRO38901, interleukin 17 receptor C, IL17-RL, IL17RL) Copy Product InfoSynonyms: UNQ6118/PRO20040/PRO38901, interleukin 17 receptor C, IL17-RL, IL17RL
Catalog No. TMPY-02691 Copy Product Info
IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.3 kDa and the accession number is Q8NAC3-3.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $68 | 7-10 days | 7-10 days | |
| 10 µg | $108 | 7-10 days | 7-10 days | |
| 20 µg | $178 | 7-10 days | 7-10 days | |
| 50 µg | $359 | 7-10 days | 7-10 days | |
| 100 µg | $696 | 7-10 days | 7-10 days | |
| 200 µg | $1,060 | 7-10 days | 7-10 days | |
| 500 µg | $2,230 | 7-10 days | 7-10 days | |
| 1 mg | $4,530 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured by its binding ability in a functional ELISA. Immobilized Human IL17 at 2 μg/ml (100 μl/well) can bind Human IL17RC hFc , the EC50 of Human IL17RC hFc is 200-800 ng/mL. |
| Description | IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.3 kDa and the accession number is Q8NAC3-3. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q8NAC3-3 |
| Construction | A DNA sequence encoding the extracellular domain of human IL17RC isoform 3 (NP_116121.2) (Met 1-Ala 454) was fused with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Leu 21 |
| Protein Purity | > 95 % as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Synonyms | UNQ6118/PRO20040/PRO38901, interleukin 17 receptor C, IL17-RL, IL17RL |
| Research Background | IL17RC (Interleukin 17 Receptor C) is a Protein Coding gene. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). IL17RC is widely expressed in the prostate, skin, and other tissues. The hypomethylation within the IL17RC gene promoter in peripheral blood is not suitable for use as a clinical biomarker of AMD. This study highlights the need for considerable replication of epigenetic association studies before clinical application. methylation of IL17RC could play as a marker in choroidal neovascularization (CNV) and degeneration of retinal pigment epithelium (RPE) cells in vitro. Diseases associated with IL17RC include Candidiasis, Familial, 9, and Chronic Mucocutaneous Candidiasis. |
| Molecular Weight | 75.3 kDa (predicted); 100-120 kDa (reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) chemical structure | IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) molecular weight
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