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IL-17RC Protein, Human, Recombinant(aa 1-454, hFc)

Catalog No. TMPY-02691
Synonyms: IL17RL, interleukin 17 receptor C, UNQ6118/PRO20040/PRO38901, IL17-RL

IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.3 kDa and the accession number is Q8NAC3-3.

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IL-17RC Protein, Human, Recombinant(aa 1-454, hFc)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 600.00
1 mg 5 days $ 3,910.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.3 kDa and the accession number is Q8NAC3-3.
Species Human
Expression System HEK293 Cells
Tag C-hFc
Accession Number Q8NAC3-3
Synonyms IL17RL, interleukin 17 receptor C, UNQ6118/PRO20040/PRO38901, IL17-RL
Construction The extracellular domain of Human IL17RC isoform 3 (NP_116121.2) (Met 1-Ala 454) was fused with the Fc region of Human IgG1 at the C-terminus.
Protein Purity > 95 % as determined by SDS-PAGE
Molecular Weight 75.3 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background IL17RC (Interleukin 17 Receptor C) is a Protein Coding gene. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). IL17RC is widely expressed in the prostate, skin, and other tissues. The hypomethylation within the IL17RC gene promoter in peripheral blood is not suitable for use as a clinical biomarker of AMD. This study highlights the need for considerable replication of epigenetic association studies before clinical application. methylation of IL17RC could play as a marker in choroidal neovascularization (CNV) and degeneration of retinal pigment epithelium (RPE) cells in vitro. Diseases associated with IL17RC include Candidiasis, Familial, 9, and Chronic Mucocutaneous Candidiasis.

References and Literature

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Keywords

IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) IL17RL interleukin 17 receptor C UNQ6118/PRO20040/PRO38901 UNQ6118/PRO20040/PRO-38901 IL17-RL UNQ6118/PRO20040/PRO 38901 recombinant recombinant-proteins proteins protein

 

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