Claudin-4 Protein-VLP, Human, Recombinant

Name: Claudin-4 Protein-VLP, Human, Recombinant
Brand: TargetMol
SKU: TMPK-00710
Rating: 4.5 (1 reviews)

(Synonyms: WBSCR8, CPETR1, CPE-R, CPE R, CLDN4, Claudin-4, Claudin4) Copy Product Info

Synonyms: WBSCR8, CPETR1, CPE-R, CPE R, CLDN4, Claudin-4, Claudin4

Catalog No. TMPK-00710 Copy Product Info

Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.

Claudin-4 Protein-VLP, Human, Recombinant

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
10 µg	$286	7-10 days	7-10 days
20 µg	$478	7-10 days	7-10 days
50 µg	$957	7-10 days	7-10 days
100 µg	$1,620	7-10 days	7-10 days
200 µg	$2,930	7-10 days	7-10 days
500 µg	$6,520	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human Claudin 4 VLP at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA.
Description	Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.
Species	Human
Expression System	HEK293 Cells
Accession Number	O14493
Construction	Met1-Val209
Protein Purity	> 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant.
Synonyms	WBSCR8, CPETR1, CPE-R, CPE R, CLDN4, Claudin-4, Claudin4
Research Background	Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.

Chemical Properties

Molecular Weight

23.31 kDa (predicted)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.