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Acipimox

Name: Acipimox
Brand: TargetMol
SKU: T1162
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T1162Cas No. 51037-30-0

Alias Olbemox, K-9321

Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.

Acipimox

🥰Excellent

Purity: 98.98%

Catalog No. T1162Alias Olbemox, K-9321Cas No. 51037-30-0

Pack Size	Price	Availability
25 mg	$30	In Stock
50 mg	$39	In Stock
100 mg	$58	In Stock
500 mg	$143	In Stock

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Batch Information

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Purity:98.98%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.
Synonyms	Olbemox, K-9321

Chemical Properties

Molecular Weight	154.12
Formula	C₆H₆N₂O₃
Cas No.	51037-30-0
Smiles	C(O)(=O)C=1C=N(=O)C(C)=CN1
Relative Density.	1.44 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (324.42 mM), Sonication is recommended.

H2O: 15.4 mg/mL (99.92 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	6.4885 mL	32.4423 mL	64.8845 mL	324.4225 mL
5 mM	1.2977 mL	6.4885 mL	12.9769 mL	64.8845 mL
10 mM	0.6488 mL	3.2442 mL	6.4885 mL	32.4423 mL
20 mM	0.3244 mL	1.6221 mL	3.2442 mL	16.2211 mL
50 mM	0.1298 mL	0.6488 mL	1.2977 mL	6.4885 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0649 mL	0.3244 mL	0.6488 mL	3.2442 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc