TCblR Protein, Human, Recombinant (hFc)

Name: TCblR Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-01344
Rating: 4.5 (1 reviews)

(Synonyms: Transcobalamin receptor, TCblR, FDC-SM-8D6, FDC-signaling molecule 8D6, CD320 antigen, CD320, 8D6 antigen) Copy Product Info

Synonyms: Transcobalamin receptor, TCblR, FDC-SM-8D6, FDC-signaling molecule 8D6, CD320 antigen, CD320, 8D6 antigen

Catalog No. TMPJ-01344 Copy Product Info

TCblR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 58-60 KDa and the accession number is Q9NPF0.

Pack Size	Price	USA Stock	Global Stock
5 µg	$72	7-10 days	7-10 days
10 µg	$116	7-10 days	7-10 days
20 µg	$176	7-10 days	7-10 days
50 µg	$310	7-10 days	7-10 days
100 µg	$532	7-10 days	7-10 days
200 µg	$919	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	TCblR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 58-60 KDa and the accession number is Q9NPF0.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q9NPF0
Amino Acid	Ser36-Val231
Construction	Ser36-Val231
Protein Purity	Greater than 85% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Transcobalamin receptor, TCblR, FDC-SM-8D6, FDC-signaling molecule 8D6, CD320 antigen, CD320, 8D6 antigen
Research Background	CD320 antigen is also known as 8D6 antigen，FDC-signaling molecule 8D6，Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.

Chemical Properties

Molecular Weight

58-60 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.