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Synonyms: Ubiquitin-Protein Ligase D4, Ubiquitin-Conjugating Enzyme E2 D4, Ubiquitin Carrier Protein D4, UBE2D4, UBCH5D, HBUCE1

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 μg | $35 | 35 days | 35 days | |
| 20 μg | $51 | 35 days | 35 days | |
| 50 μg | $91 | 35 days | 35 days | |
| 100 μg | $168 | 35 days | 35 days | |
| 200 μg | $325 | 35 days | 35 days | |
| 500 μg | $781 | 35 days | 35 days | |
| 1 mg | $1,120 | 35 days | 35 days |
| Description | Ubiquitin-Conjugating Enzyme E2 D4 (UBE2D4) is a ligase that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2D4 has been proposed to participate in Ubl conjugation pathway. UBE2D4 takes part in post-translational protein modification, protein K6-linked ubiquitination, protein K11-linked ubiquitination, protein K27-linked ubiquitination, protein K29-linked ubiquitination, protein K48-linked ubiquitination, and protein K63-linked ubiquitination. UBE2D4 regulate of protein metabolic process. UBE2D4 accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBE2D4 able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11' and 'Lys-48'-linked poly-ubiquitination. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-GST |
| Accession Number | Q9Y2X8 |
| Amino Acid | Met1-Met147 |
| Construction | Met1-Met147 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Ubiquitin-Protein Ligase D4, Ubiquitin-Conjugating Enzyme E2 D4, Ubiquitin Carrier Protein D4, UBE2D4, UBCH5D, HBUCE1 |
| Research Background |
| Molecular Weight | 40 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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