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Hydrocortisone aceponate

Name: Hydrocortisone aceponate
Brand: TargetMol
SKU: T32114
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T32114Cas No. 74050-20-7

Alias Suniderma, Hydrocortisone 17-propionate 21-acetate, Efficort

Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is an effective topical glucocorticoid cream used to treat various skin diseases.

Hydrocortisone aceponate

🥰Excellent

Purity: 98.12%

Catalog No. T32114Alias Suniderma, Hydrocortisone 17-propionate 21-acetate, EfficortCas No. 74050-20-7

Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is an effective topical glucocorticoid cream used to treat various skin diseases.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$33	In Stock	In Stock
25 mg	$58	In Stock	In Stock
50 mg	$95	In Stock	In Stock
100 mg	$142	In Stock	In Stock
200 mg	$198	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.12%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is an effective topical glucocorticoid cream used to treat various skin diseases.
Targets&IC50	IL-6:6.7 μM
Synonyms	Suniderma, Hydrocortisone 17-propionate 21-acetate, Efficort

Chemical Properties

Molecular Weight	460.56
Formula	C₂₆H₃₆O₇
Cas No.	74050-20-7
Smiles	[H][C@@]12CC[C@](OC(=O)CC)(C(=O)COC(C)=O)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
Relative Density.	1.23g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (195.41 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 5 mg/mL (10.86 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1713 mL	10.8563 mL	21.7127 mL	108.5635 mL
5 mM	0.4343 mL	2.1713 mL	4.3425 mL	21.7127 mL
10 mM	0.2171 mL	1.0856 mL	2.1713 mL	10.8563 mL
20 mM	0.1086 mL	0.5428 mL	1.0856 mL	5.4282 mL
50 mM	0.0434 mL	0.2171 mL	0.4343 mL	2.1713 mL
100 mM	0.0217 mL	0.1086 mL	0.2171 mL	1.0856 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc