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Midkine Protein, Mouse, Recombinant (His)

(Synonyms: NEGF2, MKARAP, MK1, MK, MEK, MDK, ARAP) Copy Product Info

Synonyms: NEGF2, MKARAP, MK1, MK, MEK, MDK, ARAP

Catalog No. TMPK-00812 Copy Product Info
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 14.03 kDa and the accession number is P12025.

Batch Information

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Purity:> 95% as determined by Bis-Tris PAGE
Color:Transparent
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Product Introduction

Bioactivity
Description
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 14.03 kDa and the accession number is P12025.
Species
Mouse
Expression System
E. coli
TagN-His
Accession NumberP12025
ConstructionLys23-Asp140
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in PBS, 350 mM NaCl, 200 mM L-arginine (pH 7.4).
Stability & StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsNEGF2, MKARAP, MK1, MK, MEK, MDK, ARAP
Research Background
Chemical Properties
Molecular Weight14.03 kDa (predicted). The protein migrates to 17-20 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: Midkine Protein, Mouse, Recombinant (His) chemical structure | Midkine Protein, Mouse, Recombinant (His) molecular weight