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Anti-FUNDC1 Polyclonal Antibody is a Rabbit antibody targeting FUNDC1. Anti-FUNDC1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
| Description | Anti-FUNDC1 Polyclonal Antibody is a Rabbit antibody targeting FUNDC1. Anti-FUNDC1 Polyclonal Antibody can be used in WB. |
| Synonyms | FUND1, FUN14 domain containing protein 1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | Sample: Lane 1: Mouse Cerebellum tissue lysates Lane 2: Mouse Heart tissue lysates Lane 3: Human 293T cell lysates Lane 4: Human MCF-7 cell lysates Lane 5: Human A549 cell lysates Primary: Anti-FUNDC1 (TMAB-00720) at 1/800 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 17 kDa Observed band size: 17 kDa ![]() |
| Application | |
| Recommended Dose | WB=1:300-800 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion outer membrane; Multi-pass membrane protein. |
| Tissue Specificity | Widely expressed. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | FUNDC1 is a 155 amino acid protein belonging to the FUN14 family. The gene encoding FUNDC1 maps to human chromosome Xp11.3 and mouse chromosome X A1.2. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. |
| Immunogen | KLH conjugated synthetic peptide: mouse FUNDC1 |
| Antigen Species | Mouse |
| Gene Name | FUNDC1 |
| Gene ID | |
| Protein Name | FUN14 domain-containing protein 1 |
| Uniprot ID | |
| Biology Area | Other Antibodies |
| Function | Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control. |
| Molecular Weight | Theoretical: 17 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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