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Anti-XBP1 Antibody (8M292)

(Synonyms: XBP2, XBP-1, XBP1, XBP 1, X-box-binding protein 1, luminal form, X-box-binding protein 1, cytoplasmic form, X-box-binding protein 1 in isoform 2, X box-binding protein-1, X box binding protein 2, TREB5, Tax responsive element binding protein 5) Copy Product Info
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Synonyms: XBP2, XBP-1, XBP1, XBP 1, X-box-binding protein 1, luminal form, X-box-binding protein 1, cytoplasmic form, X-box-binding protein 1 in isoform 2, X box-binding protein-1, X box binding protein 2, TREB5, Tax responsive element binding protein 5

Catalog No. TMAC-04296 Copy Product Info
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Anti-XBP1 Antibody (8M292) is a Rabbit antibody targeting XBP1. Anti-XBP1 Antibody (8M292) can be used in FCM,ICC/IF,IHC,WB.
Anti-XBP1 Antibody
(8M292)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-XBP1 Antibody (8M292) is a Rabbit antibody targeting XBP1. Anti-XBP1 Antibody (8M292) can be used in FCM,ICC/IF,IHC,WB.
SynonymsXBP2, XBP-1, XBP1, XBP 1, X-box-binding protein 1, luminal form, X-box-binding protein 1, cytoplasmic form, X-box-binding protein 1 in isoform 2, X box-binding protein-1, X box binding protein 2, TREB5, Tax responsive element binding protein 5
Ig Type
IgG
Clone
8M292
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:100-500; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe X-box binding protein-1 (XBP-1 or hXBP-1), also designated tax-responsive element-binding protein 5 (TREB5) in mouse and human, or hepatocarcinogenesis-related transcription factor (HTF) in rat, belongs to the basic region/leucine zipper (bZIP) family of transcription factors. XBP-1 was first characterized as a protein that binds to the HLA-DRα promoter in B cells. XBP-1 recognizes the cAMP responsive element (CRE) in enhancers of human T cell leukemia virus and major histocompatibility complex class II genes and activates transcription of these genes. It is expressed at high levels in developing bone and its levels are modulated during osteoblast development, suggesting a role in regulation of expression of osteoblast-specific genes. In addition to binding to CRE sequences, XBP-1 has been shown to bind to TPA response elements (TREs).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 40 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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