GITR Ligand/TNFSF18 Protein, Mouse, Recombinant

Name: GITR Ligand/TNFSF18 Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPS-00164
Price: 85 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: TNFSF18, TL-6, GITRL, Activation-induced TNFR member Ligand) Copy Product Info

Synonyms: TNFSF18, TL-6, GITRL, Activation-induced TNFR member Ligand

Catalog No. TMPS-00164 Copy Product Info

GITR Ligand/TNFSF18 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is Q7TS55.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$85	-	In Stock
10 µg	$138	-	In Stock
20 µg	$238	7-10 days	7-10 days
50 µg	$497	-	In Stock
100 µg	$833	7-10 days	7-10 days
200 µg	$1,380	7-10 days	7-10 days
500 µg	$2,790	7-10 days	7-10 days
1 mg	$4,750	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 5.0 ng/ml, measured by the amount of Interleukin-8 produced by PMBC, corresponding to a specific activity of > 2.0 × 10 5 units/mg.
Description	GITR Ligand/TNFSF18 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is Q7TS55.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	Q7TS55
Construction	Thr47-Ser173
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TNFSF18, TL-6, GITRL, Activation-induced TNFR member Ligand
Research Background	Activation-Inducible TNF-Related Ligand (AITRL), also known as Glucocorticoid-Induced TNF-Related Ligand (GITRL), belongs to the tumor necrosis factor superfamily (TNFSF). AITRL is a Type II single transmembrane protein and shares low conservation within the extracellular domain with other TNFSF members. AITRL is expressed on macrophages, immature and mature dendritic cells and B cells. Its receptor, Activation-Inducible TNFR family Receptor (AITR), is expressed on T lymphocytes, natural killer (NK) cells, and antigen- presenting cells. After binding by AITRL, AITR can be released. AITR activation increases resistance to tumors and viral infections and is involved in autoimmune and inflammatory processes. In addition, activated AITR increases TCR-induced T cell proliferation and cytokine production and rescues T cells and NK cells from apoptosis.

Chemical Properties

Molecular Weight

~14.5 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.