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Isonipecotic acid

Name: Isonipecotic acid
Brand: TargetMol
SKU: T22348
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22348Cas No. 498-94-2

Alias Hexahydroisonicotinic acid, 4-Piperidinecarboxylic acid, 4-Carboxypiperidine

Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.

Isonipecotic acid

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Purity: 99.82%

Catalog No. T22348Alias Hexahydroisonicotinic acid, 4-Piperidinecarboxylic acid, 4-CarboxypiperidineCas No. 498-94-2

Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.82%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Isonipecotic acid (4-Piperidinecarboxylic acid) is a heterocyclic compound. Isonipecotic acid mainly characterized as a GABAA receptor partial agonist.
Synonyms	Hexahydroisonicotinic acid, 4-Piperidinecarboxylic acid, 4-Carboxypiperidine

Chemical Properties

Molecular Weight	129.16
Formula	C₆H₁₁NO₂
Cas No.	498-94-2
Smiles	OC(=O)C1CCNCC1
Relative Density.	1.125 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 25 mg/mL (193.56 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	7.7423 mL	38.7117 mL	77.4234 mL	387.1168 mL
5 mM	1.5485 mL	7.7423 mL	15.4847 mL	77.4234 mL
10 mM	0.7742 mL	3.8712 mL	7.7423 mL	38.7117 mL
20 mM	0.3871 mL	1.9356 mL	3.8712 mL	19.3558 mL
50 mM	0.1548 mL	0.7742 mL	1.5485 mL	7.7423 mL
100 mM	0.0774 mL	0.3871 mL	0.7742 mL	3.8712 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc