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2-(Hydroxymethyl)pyridine

Name: 2-(Hydroxymethyl)pyridine
Brand: TargetMol
SKU: T1112
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1112Cas No. 586-98-1

Alias Piconol

2-(Hydroxymethyl)pyridine (Piconol) is used as an organic synthesis and medicinal chemistry intermediate for the synthesis of the stimulant laxative bisacodyl, and as a pyridinol with hypoglycemic activity.

2-(Hydroxymethyl)pyridine

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Purity: 99.79%

Catalog No. T1112Alias PiconolCas No. 586-98-1

Pack Size	Price	Availability	Quantity
1 g	$29	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.79%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	2-(Hydroxymethyl)pyridine (Piconol) is used as an organic synthesis and medicinal chemistry intermediate for the synthesis of the stimulant laxative bisacodyl, and as a pyridinol with hypoglycemic activity.
Synonyms	Piconol

Chemical Properties

Molecular Weight	109.13
Formula	C₆H₇NO
Cas No.	586-98-1
Smiles	OCC1=NC=CC=C1
Relative Density.	1.131g/mLat 25°C(lit.)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (458.17 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	9.1634 mL	45.8169 mL	91.6338 mL	458.1692 mL
5 mM	1.8327 mL	9.1634 mL	18.3268 mL	91.6338 mL
10 mM	0.9163 mL	4.5817 mL	9.1634 mL	45.8169 mL
20 mM	0.4582 mL	2.2908 mL	4.5817 mL	22.9085 mL
50 mM	0.1833 mL	0.9163 mL	1.8327 mL	9.1634 mL
100 mM	0.0916 mL	0.4582 mL	0.9163 mL	4.5817 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc