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Adrenocorticotropic Hormone (ACTH) (4-10) TFA

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Catalog No. T7627L
Alias Adrenocorticotropic Hormone (ACTH) (4-10) TFA(4037-01-8(free base)), Acth (4-10)

Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) is an agonist of potent melanocortin(MC4R) receptor .

Adrenocorticotropic Hormone (ACTH) (4-10) TFA

Adrenocorticotropic Hormone (ACTH) (4-10) TFA

😃Good
Purity: 98.49%
Catalog No. T7627LAlias Adrenocorticotropic Hormone (ACTH) (4-10) TFA(4037-01-8(free base)), Acth (4-10)
Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) is an agonist of potent melanocortin(MC4R) receptor .
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$52In StockIn Stock
2 mg$68In StockIn Stock
5 mg$98In StockIn Stock
10 mg$163In StockIn Stock
25 mg$359In StockIn Stock
50 mg$539In StockIn Stock
100 mg$688In StockIn Stock
200 mg$996-In Stock
1 mL x 10 mM (in DMSO)$225In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.49%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) is an agonist of potent melanocortin(MC4R) receptor .
In vivo
In humans, Adrenocorticotropic Hormone (ACTH) (4-10)?enters the cerebral fluid compartment after intranasal application and leads to a?decrease in total body fat after 6 weeks of continuous treatment[1].
SynonymsAdrenocorticotropic Hormone (ACTH) (4-10) TFA(4037-01-8(free base)), Acth (4-10)
Chemical Properties
Molecular Weight1076.12
FormulaC46H60F3N13O12S
SmilesOC(=O)C(F)(F)F.CSCC[C@H](N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(O)=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (51.11 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.9293 mL4.6463 mL9.2926 mL46.4632 mL
5 mM0.1859 mL0.9293 mL1.8585 mL9.2926 mL
10 mM0.0929 mL0.4646 mL0.9293 mL4.6463 mL
20 mM0.0465 mL0.2323 mL0.4646 mL2.3232 mL
50 mM0.0186 mL0.0929 mL0.1859 mL0.9293 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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