Shopping Cart
Remove All
Your shopping cart is currently empty
Peruvoside
Copy Product Info
😃Good
Catalog No. T126270Cas No. 1182-87-2
Alias Encordin
Peruvoside (Encordin) is a natural cardiac glycoside that inhibits Na+/K+-ATPase to increase myocardial contractility; causes cell cycle arrest in leukemia stem cells at the G₂/M phase, and; inhibits NSCLC cell growth as a Src inhibitor; and induces apoptosis in cancer cells through MAPK Wnt / β-catenin and PI3K / AKT / mTOR .
Peruvoside
Copy Product Info😃Good
Catalog No. T126270Alias EncordinCas No. 1182-87-2
Peruvoside (Encordin) is a natural cardiac glycoside that inhibits Na+/K+-ATPase to increase myocardial contractility; causes cell cycle arrest in leukemia stem cells at the G₂/M phase, and; inhibits NSCLC cell growth as a Src inhibitor; and induces apoptosis in cancer cells through MAPK Wnt / β-catenin and PI3K / AKT / mTOR .
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $213 | 7-10 days | 7-10 days | |
| 5 mg | $645 | 7-10 days | 7-10 days |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Appearance:Solid
Color:White
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Peruvoside (Encordin) is a natural cardiac glycoside that inhibits Na+/K+-ATPase to increase myocardial contractility; causes cell cycle arrest in leukemia stem cells at the G₂/M phase, and; inhibits NSCLC cell growth as a Src inhibitor; and induces apoptosis in cancer cells through MAPK Wnt / β-catenin and PI3K / AKT / mTOR . |
| In vitro | Methods: A549 lung cancer cell line was treated with Peruvoside (5, 10, 50 nM, 24 hours), and the expression of related proteins was analyzed by Western Blot. Results: Peruvoside inhibited the protein expression and phosphorylation of Src, EGFR and STAT3 in A549 cells. [1] |
| In vivo | Methods: Nude mice with A549 cell subcutaneous xenografts were treated with Peruvoside (0.1 mg/kg, intraperitoneal injection, daily, for 28 days). Tumor growth was then monitored every 7 days. Results: The mean tumor size in the Peruvoside-treated group was 129.9 mm³ (95% CI = 86-174 mm³; P = 0.0068), which was significantly smaller than that in the control group (348 mm³, 95% CI = 189-507 mm³). The tumor weight was also significantly reduced, from 0.55 g in the control group to 0.26 g in the Peruvoside-treated group (P = 0.0126). [1] |
| Synonyms | Encordin |
| Molecular Weight | 548.67 |
| Formula | C30H44O9 |
| Cas No. | 1182-87-2 |
| Smiles | C(=O)[C@@]12[C@@]3([C@]([C@]4(O)[C@](C)(CC3)[C@H](CC4)C=5COC(=O)C5)(CC[C@@]1(C[C@@H](O[C@H]6[C@@H](O)[C@H](OC)[C@@H](O)[C@H](C)O6)CC2)[H])[H])[H] |
| Storage | keep away from moisture,keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 200 mg/mL (364.52 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Peruvoside | purchase Peruvoside | Peruvoside cost | order Peruvoside | Peruvoside chemical structure | Peruvoside in vivo | Peruvoside in vitro | Peruvoside formula | Peruvoside molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.