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Phycocyanobilin

Name: Phycocyanobilin
Brand: TargetMol
SKU: T73944
Rating: 4.5 (1 reviews)

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Catalog No. T73944Cas No. 20298-86-6

Phycocyanobilin (PCB), a linear open-chain tetrapyrrole chromophore, is a bilirubin analog with anti-inflammatory and antioxidant activity for the study of neurological disorders such as Alzheimer's disease.

Phycocyanobilin

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Purity: 98.16%

Catalog No. T73944Cas No. 20298-86-6

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.16%

Appearance:Solid

Color:Green to Black

Resource Download

COA LCMS

Product Introduction

Bioactivity

Description	Phycocyanobilin (PCB), a linear open-chain tetrapyrrole chromophore, is a bilirubin analog with anti-inflammatory and antioxidant activity for the study of neurological disorders such as Alzheimer's disease.
In vivo	Antioxidant effects were observed after oral administration of phycocyanobilin (15 mg/kg) for 2 weeks； Phycocyanobilin also inhibited NADPH-dependent superoxide production in cultured renal mesangial cells. [1]

Chemical Properties

Molecular Weight	586.68
Formula	C₃₃H₃₈N₄O₆
Cas No.	20298-86-6
Smiles	C(\C1=C(CCC(O)=O)C(C)=C(/C=C\2/C(=C/C)/[C@@H](C)C(=O)N2)N1)=C3/C(CCC(O)=O)=C(C)C(/C=C\4/C(C)=C(CC)C(=O)N4)=N3

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Methanol: Insoluble

DMSO: 1 mg/mL (1.7 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7045 mL	8.5225 mL	17.0451 mL	85.2253 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc