Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TargetMol | Compound Library

JAK-STAT Compound Library

Catalog No. L3700

Cell signal transduction is the transmission of molecular signals via various proteins in a signaling cascade, which carries and amplifies the signal. The JAK-STAT signaling pathway communicates information from chemical signals outside of a cell to the cell nucleus, resulting in the activation of genes through a process called transcription. There are three key parts of JAK-STAT signaling: Janus kinases (JAKs), Signal Transducer and Activator of Transcription proteins (STATs), and receptors (which bind the chemical signals). JAK-STAT signaling pathway is a chain of interactions between proteins in a cell, and is involved in processes such as immunity, cell division, cell death and tumor formation. Disrupted JAK-STAT signaling may lead to a variety of diseases, such as skin conditions, cancers, and disorders affecting the immune system. There are 4 JAK proteins: JAK1, JAK2, JAK3 and TYK2, and there are 7 STAT proteins: STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B and STAT6. JAK/STAT Compound Library from TargetMol, a unique collection of 415 compounds targeting JAK/STAT signaling, can be used for research in JAK/STAT signaling and related drug screening (high throughput and high content screening).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Resource Download
Library compound info
Excel
SDF
Contact us for more batch information

Catalog No. L3700

JAK-STAT Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
Inquiry & Custom

Top Publication Citing
Use of TargetMol Products

Cite scientific literature on TargetMol products

View More

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • A unique collection of 415 JAK/STAT signaling targeted compounds for high throughput and high content screening;
  • Effective tool for studying the JAK/STAT targets;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
Inquiry & Custom

Sci Citations

Library Customization | TargetMol Library Composition

EGFR
JAK
Apoptosis
STAT
Autophagy
Potassium Channel
HER
Tyrosine Kinases
Pim
FLT
NF-κB
VEGFR
Src
CDK
FGFR
Endogenous Metabolite
p38 MAPK
PDGFR
Akt
c-Met/HGFR
Parasite
Antibacterial
ERK
Bcr-Abl
COX
HIV Protease
IGF-1R
Bcl-2 Family
5-HT Receptor
PI3K
IL Receptor
c-RET
TNF
Ras
BTK
Ferroptosis
Caspase
Calcium Channel
Drug Metabolite
Aurora Kinase
Cytochromes P450
mTOR
Interleukin
Influenza Virus
IκB/IKK
AMPK
MEK
c-Kit
Sodium Channel
Antibiotic
Histone Methyltransferase
JNK
PKA
PKC
Reactive Oxygen Species
DNA/RNA Synthesis
HSP
TLR
ALK
c-Fms
AChR
Syk
GPCR
HCV Protease
Integrin
Antioxidant
DYRK
Histamine Receptor
Phosphatase
Mitophagy
Virus Protease
Wnt/beta-catenin
Topoisomerase
RIP kinase
Raf
Antifection
Somatostatin
Epigenetic Reader Domain
TGF-beta/Smad
Survivin
P-gp
Histone Acetyltransferase
Casein Kinase
Hippo pathway
Beta Amyloid
HDAC
DNA Methyltransferase
FAK
HIF/HIF Prolyl-Hydroxylase
ROS Kinase
MLK
NO Synthase
Melanin-concentrating Hormone Receptor (MCHR)
Proton pump
Dopamine Receptor
Antifungal
Na+/Ca2+ Exchanger
IFNAR
GTPase
GSK-3
OCT
c-Myc
Estrogen Receptor/ERR
HBV
Cholecystokinin Receptor
PARP
Serine/threonin kinase
Nucleoside Antimetabolite/Analog
Cysteine Protease
PYK2
TRP/TRPV Channel
ROCK
Adrenergic Receptor
CSF-1R
UGT
PDE
Gamma-secretase
NMDAR
ROS
FAAH
CCR
ACK1
PTEN
MMP
Chk
cAMP
GluR
Thrombopoietin Receptor
CaMK
DUB
MAPK
MNK
Antiviral
Trk receptor
Sirtuin
Ephrin Receptor
hCE
MELK
RSV
ATM/ATR
Reverse Transcriptase
KRas
GABA Receptor
PLK
HIF
SGK
DAPK
Anti-infection
NADPH-oxidase
IRAK
S6 Kinase
Sigma receptor
Tyrosinase
PD-1/PD-L1
Monoamine Oxidase

Keywords