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Trilobatin

Name: Trilobatin
Brand: TargetMol
SKU: T2S0731
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2S0731Cas No. 4192-90-9

Alias P-Phlorizin

Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory response by suppressing the NF-κB signaling pathway.Trilobatin shows a strong inhibitory activity against α-glucosidase and a moderate inhibitory activity against α-amylase for management of postprandial hyperglycemia with less side effect.

Trilobatin

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Purity: 97.16%

Catalog No. T2S0731Alias P-PhlorizinCas No. 4192-90-9

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	In Stock	In Stock
5 mg	$106	In Stock	In Stock
10 mg	$152	In Stock	In Stock
25 mg	$289	In Stock	In Stock
50 mg	$428	In Stock	In Stock
100 mg	$619	In Stock	In Stock
200 mg	$877	-	In Stock
1 mL x 10 mM (in DMSO)	$117	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.16%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Trilobatin AI Summary

Trilobatin exhibits low binding affinity to human recombinant CNT3, as evidenced by [3H]uridine uptake in pig PK15NTD cells with a Ki value greater than 100,000.0 nM. It demonstrates antibacterial activity with a Minimum Inhibitory Concentration (MIC) of 500.0 µg/mL against Staphylococcus aureus ATCC 6538 and 1500.0 µg/mL against Escherichia coli ATCC 10536. Additionally, Trilobatin has notable antioxidant activity, with a DPPH radical scavenging capacity equivalent to 0.89 mg of BHT..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Synonyms

P-Phlorizin

Chemical Properties

Molecular Weight	436.41
Formula	C₂₁H₂₄O₁₀
Cas No.	4192-90-9
Smiles	OC[C@H]1O[C@@H](Oc2cc(O)c(C(=O)CCc3ccc(O)cc3)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O
Relative Density.	1.555g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 240 mg/mL (549.94 mM), Sonication is recommended.

Ethanol: Soluble

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.58 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2914 mL	11.4571 mL	22.9142 mL	114.5712 mL
5 mM	0.4583 mL	2.2914 mL	4.5828 mL	22.9142 mL
10 mM	0.2291 mL	1.1457 mL	2.2914 mL	11.4571 mL
20 mM	0.1146 mL	0.5729 mL	1.1457 mL	5.7286 mL
50 mM	0.0458 mL	0.2291 mL	0.4583 mL	2.2914 mL
100 mM	0.0229 mL	0.1146 mL	0.2291 mL	1.1457 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc