ANGPTL3 Protein, Human, Recombinant (His & Avi)

Name: ANGPTL3 Protein, Human, Recombinant (His & Avi)
Brand: TargetMol
SKU: TMPK-00284
Rating: 4.5 (1 reviews)

(Synonyms: FHBL2, ANL3, ANGPTL3, ANGPT5, Angiopoietin-like Protein 3, Angiopoietin-5, ANG-5) Copy Product Info

Synonyms: FHBL2, ANL3, ANGPTL3, ANGPT5, Angiopoietin-like Protein 3, Angiopoietin-5, ANG-5

Catalog No. TMPK-00284 Copy Product Info

ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. ANGPTL3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.6 kDa and the accession number is Q9Y5C1.

ANGPTL3 Protein, Human, Recombinant (His & Avi)

Pack Size	Price	USA Stock	Global Stock
5 µg	$46	7-10 days	7-10 days
10 µg	$72	7-10 days	7-10 days
20 µg	$115	7-10 days	7-10 days
50 µg	$222	7-10 days	7-10 days
100 µg	$371	7-10 days	7-10 days
200 µg	$673	7-10 days	7-10 days
500 µg	$1,490	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1. Immobilized Human ANGPTL3, His Tag at 0.5μg/ml (100μl/Well). Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 8.2ng/ml determined by ELISA. 2. Human LILRB2 captured on Protein A chip, can bind Human ANGPTL3, His Tag with an affinity constant of 17.6nM as determined in a SPR assay.
Description	ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. ANGPTL3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.6 kDa and the accession number is Q9Y5C1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	Q9Y5C1
Construction	Ser17-Lys219
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	FHBL2, ANL3, ANGPTL3, ANGPT5, Angiopoietin-like Protein 3, Angiopoietin-5, ANG-5
Research Background	ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake.

Chemical Properties

Molecular Weight

26.6 kDa (predicted). Due to glycosylation, the protein migrates to 30-38 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.