CD122/IL2RB Protein, Mouse, Recombinant (His)

Name: CD122/IL2RB Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-04031
Price: 67 EUR
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: p70, interleukin 2 receptor, β, interleukin 2 receptor, beta, Il-2Rβ, Il-2Rbeta, Il-2/15Rβ, Il-2/15Rbeta, IL-15Rβ, IL15Rβ, IL-15Rbeta, IL15Rbeta, CD122) Copy Product Info

Synonyms: p70, interleukin 2 receptor, β, interleukin 2 receptor, beta, Il-2Rβ, Il-2Rbeta, Il-2/15Rβ, Il-2/15Rbeta, IL-15Rβ, IL15Rβ, IL-15Rbeta, IL15Rbeta, CD122

Catalog No. TMPY-04031 Copy Product Info

CD122/IL2RB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P16297.

Pack Size	Price	EUR Stock	Global Stock
5 µg	67 €	-	In Stock
10 µg	106 €	-	In Stock
20 µg	176 €	-	In Stock
50 µg	347 €	-	In Stock
100 µg	575 €	7-10 days	7-10 days
200 µg	954 €	7-10 days	7-10 days
500 µg	1.854 €	7-10 days	7-10 days

For In stock only · Estimated delivery: EUR Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:SDS-PAGE: 98.2%; SEC-HPLC: 95.3%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CD122/IL2RB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P16297.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P16297
Construction	A DNA sequence encoding the mouse IL2RB (P16297) (Met1-Glu240) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Ala 27
Protein Purity	≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. ,
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	p70, interleukin 2 receptor, β, interleukin 2 receptor, beta, Il-2Rβ, Il-2Rbeta, Il-2/15Rβ, Il-2/15Rbeta, IL-15Rβ, IL15Rβ, IL-15Rbeta, IL15Rbeta, CD122
Research Background	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concerning the ability to bind interleukin 2. The low-affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high-affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high-affinity forms of CD122/IL-2RB are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. CD122/IL-2RB expression was restricted to the earliest B220+ cells (CD43+CD24-; prepro B cells; fraction A) that proliferate vigorously to IL-2 in the absence of any stromal cells, but not to IL-15. The high-affinity form of this receptor is expressed on activated T lymphocytes, activated B lymphocytes, and activated macrophages. CD122/IL-2RB plays a role in regulating normal lymphocyte development.

Chemical Properties

Molecular Weight

26.5 kDa (predicted); 45-54 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.