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Hypotaurine

Name: Hypotaurine
Brand: TargetMol
SKU: T5225
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5225Cas No. 300-84-5

Alias 2-Aminoethylsulfinic acid, 2-Aminoethanesulfinic acid

Hypotaurine (2-Aminoethanesulfinic acid), functioning as an intermediate in the biosynthesis of taurine from cysteine within astrocytes, acts as an endogenous inhibitory amino acid targeting the glycine receptor.

Hypotaurine

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Purity: 99.72%

Catalog No. T5225Alias 2-Aminoethylsulfinic acid, 2-Aminoethanesulfinic acidCas No. 300-84-5

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$30	In Stock	In Stock
25 mg	$46	In Stock	In Stock
50 mg	$64	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.72%

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Hypotaurine AI Summary

Hypotaurine exhibits a variety of bioactivities based on assay results. It shows potency in inhibiting the Menin-MLL interaction in MLL-related leukemias and modulates Lamin A splicing. This compound acts as an agonist of the Thyroid Stimulating Hormone Receptor, also activating intracellular cAMP concentrations. Additionally, it inhibits Tau fibril formation, Bloom's syndrome helicase (BLM), Histone Lysine Methyltransferase G9a, T. brucei phosphofructokinase, HP1-beta chromodomain interactions, and the human Apurinic/apyrimidinic Endonuclease 1 (APE1). Furthermore, it inhibits Regulator of G Protein Signaling 4 (RGS4) and enhances Arylsulfatase A (ASA1)..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Hypotaurine (2-Aminoethanesulfinic acid), functioning as an intermediate in the biosynthesis of taurine from cysteine within astrocytes, acts as an endogenous inhibitory amino acid targeting the glycine receptor.
Synonyms	2-Aminoethylsulfinic acid, 2-Aminoethanesulfinic acid

Chemical Properties

Molecular Weight	109.15
Formula	C₂H₇NO₂S
Cas No.	300-84-5
Smiles	NCCS(O)=O
Relative Density.	1.511 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 125 mg/mL (1145.21 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	9.1617 mL	45.8085 mL	91.6170 mL	458.0852 mL
5 mM	1.8323 mL	9.1617 mL	18.3234 mL	91.6170 mL
10 mM	0.9162 mL	4.5809 mL	9.1617 mL	45.8085 mL
20 mM	0.4581 mL	2.2904 mL	4.5809 mL	22.9043 mL
50 mM	0.1832 mL	0.9162 mL	1.8323 mL	9.1617 mL
100 mM	0.0916 mL	0.4581 mL	0.9162 mL	4.5809 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc