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Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody (Synonyms: TrkA (p-Y680/681), TrkA (p-Tyr680/681), p-TrkA (...)

Catalog No. TMAC-04121 Copy Product Info
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Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr680/681). Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody can be used in WB.

Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-04121
Synonyms TrkA (p-Y680/681), TrkA (p-Tyr680/681), p-TrkA (Y680/681), p-TrkA (Tyr680/681)

Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr680/681). Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody can be used in WB.

Anti-Phospho-TrkA
(Tyr680/681) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr680/681). Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody can be used in WB.
SynonymsTrkA (p-Y680/681), TrkA (p-Tyr680/681), p-TrkA (Y680/681), p-TrkA (Tyr680/681)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from Jurkat cells treated with starved using Phospho-Trk A (Tyr680/Tyr681) antibody TMAC-04121. The lane on the right is treated with the antigen-specific peptide.
verifiedActivity
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundRequired for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 680/tyrosine 681 (T-D-Y(p)-Y(p)-R-V) derived from Human Trk A
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 87 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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