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Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody
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Catalog No. TMAC-04121
Alias TrkA (p-Y680/681), TrkA (p-Tyr680/681), p-TrkA (Y680/681), p-TrkA (Tyr680/681)
Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr680/681). Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody can be used in WB.
Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody
Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody
😃Good
Catalog No. TMAC-04121Alias TrkA (p-Y680/681), TrkA (p-Tyr680/681), p-TrkA (Y680/681), p-TrkA (Tyr680/681)
Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr680/681). Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr680/681). Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody can be used in WB. |
| Synonyms | TrkA (p-Y680/681), TrkA (p-Tyr680/681), p-TrkA (Y680/681), p-TrkA (Tyr680/681) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from Jurkat cells treated with starved using Phospho-Trk A (Tyr680/Tyr681) antibody TMAC-04121. The lane on the right is treated with the antigen-specific peptide.  |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 680/tyrosine 681 (T-D-Y(p)-Y(p)-R-V) derived from Human Trk A |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 87 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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