Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TargetMol | Compound Library

Drug Repurposing Compound Library

Catalog No. L9200

Traditional de novo drug discovery and development involves an HTS campaign for de novo candidate hits and requires highly specialized screening facilities and compound libraries containing several million compounds. It is a time consuming and expensive process. As the regulation for drug safety and efficacy is increasingly getting complex, the cost of developing new drugs is keeping skyrocket. Drug repositioning, also known as old drugs for new uses, is an effective strategy to find new indications for existing drugs and has recently drawn attention and has led to several blockbuster drugs because of its high efficiency and low-cost. High-content screens, new biomarkers, noninvasive imaging techniques, and advanced in bioinformatics have created new opportunities for pursuing novel indications for approved compounds.

The Drug Repurposing Compound Library by TargetMol, containing 5120 approved and clinical drugs, which have undergone extensive preclinical studies and have well-characterized bioactivities, safety and bioavailability – properties which could dramatically accelerate drug development and optimization, is a good tool for drug repurposing and cell induction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Resource Download
Library compound info
Excel
SDF
Contact us for more batch information

Catalog No. L9200

Drug Repurposing Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
Inquiry & Custom

Top Publication Citing
Use of TargetMol Products

Cite scientific literature on TargetMol products

View More

Product Description Product Description

  • A unique collection of 5120 approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS);
  • An effective tool for discovering new with old drugs, cell induction, and new drug target screening;
  • All approved drugs collected in this library are approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), or included in the US Pharmacopeia (USP) Dictionary, the British Pharmacopoeia (BP), the European Pharmacopoeia (EP), the Japanese Pharmacopoeia (JP), or Chinese Pharmacopoeia (CP) Dictionary;
  • Covers various research areas, such as cancer, cardiovascular disease, immunology, respiratory system, etc.
  • Covers various targets, such as 5-HT Receptor, Sodium Channel, p38 MAPK, PI3K, MEK, etc.
  • Detailed compound information with structure, target, activity, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality.

Advantages Introduction Advantages Introduction

High-Standard Entry Criteria

TargetMol’s Drug Repurposing Compound Library is built on rigorous inclusion standards to ensure that every compound in the library has a well-defined structure and high purity, verified by multiple analytical techniques such as NMR, HPLC, and LC-MS. Through a multi-step screening process, we eliminate compounds with undefined structures, including mixtures and polymers, as well as non-active agents such as sunscreens, contrast agents, and inorganic substances. The library exclusively includes small-molecule drugs and drug candidates that are either FDA-approved or currently in clinical trials. Compounds that have not yet entered the clinical phase are excluded, ensuring the safety of the library and enhancing the efficiency of drug repurposing efforts. This approach helps shorten the drug development cycle. Additionally, accurate compound information and clear classification significantly improve screening efficiency and reduce unnecessary resource and time costs.

Significant Structural Diversity

TargetMol’s Drug Repurposing Compound Library exhibits remarkable structural diversity, offering substantial advantages in drug discovery. Based on MACCS fingerprint analysis, the library can be categorized into 4,017 classes, effectively covering a broad chemical space. The library includes a wide variety of compounds, ranging from simple to highly complex chemical structures. This diversity provides a wealth of possibilities for identifying lead compounds with high affinity and specificity for target proteins, significantly advancing drug innovation.

 Drug Repurposing Compound Library
Library Diversity Analysis

Diverse Compound Collection

TargetMol’s Drug Repurposing Compound Library features not only a high degree of chemical diversity but also broad representation in terms of biological functions. The library includes compounds targeting key signaling pathways such as kinases, G protein-coupled receptors (GPCRs), ion channels, and epigenetic regulators. It comprehensively covers a wide range of disease areas including cancer, immune disorders, neurological diseases, metabolic diseases, and infectious diseases. The library contains 2,800+ approved drugs and 1,800+ clinical-stage drug candidates, including 190+ natural products that have entered clinical trials and 540+ natural products approved for market use. This library offers a rich and diverse chemical space, enabling researchers to explore new therapeutic strategies and accelerate the discovery of innovative drugs.

 Drug Repurposing Compound Library
Pathways Composition
 Drug Repurposing Compound Library
Disease Types
 Drug Repurposing Compound Library  Drug Repurposing Compound Library
Compound Categories

Regular Updates to Compound Libraries

TargetMol ensures compound libraries stay at the forefront of science by regularly updating our database to include the latest approved and marketed drugs.

Flexible Packaging Options

TargetMol provides a variety of standard packaging sizes (such as 30 μL, 50 μL, 100 μL, 250 μL, and 1 mg), and offer customized packaging solutions tailored to specific needs.

Personalized Custom Services

TargetMol offers fully customized screening services, including the design and synthesis of compound libraries. Our highly flexible service is designed to efficiently meet the unique needs of scientists and researchers.

Packaging And Storage Packaging And Storage

Supporting Files | TargetMol Supporting Files

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
Inquiry & Custom

Sci Citations

Library Customization | TargetMol Library Composition

Apoptosis
Antibacterial
Autophagy
Antibiotic
Endogenous Metabolite
5-HT Receptor
Adrenergic Receptor
AChR
Parasite
Dopamine Receptor
DNA/RNA Synthesis
Histamine Receptor
COX
Potassium Channel
HIV Protease
Sodium Channel
Calcium Channel
Antifungal
VEGFR
Reactive Oxygen Species
EGFR
Topoisomerase
Cytochromes P450
SARS-CoV
PDE
NF-κB
PI3K
Glucocorticoid Receptor
Virus Protease
CDK
Influenza Virus
Estrogen/progestogen Receptor
Dehydrogenase
HCV Protease
FLT
PPAR
Ferroptosis
GABA Receptor
Microtubule Associated
JAK
FGFR
iGluR
PDGFR
Estrogen Receptor/ERR
HDAC
c-Met/HGFR
c-Kit
TNF
HBV
mTOR
Prostaglandin Receptor
RAAS
Akt
Nucleoside Antimetabolite/Analog
p38 MAPK
Androgen Receptor
Mitophagy
Interleukin
Cholinesterase (ChE)
Serotonin Transporter
Caspase
Reverse Transcriptase
HSV
Ras
Adenosine Receptor
Src
Tyrosine Kinases
TRP/TRPV Channel
NMDAR
GPCR
Bcr-Abl
ERK
Bcl-2 Family
MMP
Proteasome
HIF/HIF Prolyl-Hydroxylase
Drug Metabolite
PARP
GluR
Norepinephrine
MAO
ATPase
HSP
Progesterone Receptor
Raf
Antiviral
Beta Amyloid
Monoamine Oxidase
ROS
Antioxidant
ribosome
Phosphatase
Opioid Receptor
Epigenetic Reader Domain
STAT
Mitochondrial Metabolism
ALK
Carbonic Anhydrase
Proton pump
P-gp
AMPK
IL Receptor
TLR
Transferase
PKC
Aurora Kinase
MEK
Anti-infection
Histone Methyltransferase
MDM-2/p53
NO Synthase
DPP-4
Angiotensin-converting Enzyme (ACE)
Antifection
HER
DNA Alkylator/Crosslinker
Thyroid hormone receptor(THR)
JNK
c-RET
c-Fms
Endothelin Receptor
HMG-CoA Reductase
Nrf2
Phospholipase
LPL Receptor
GNRH Receptor
Lipoxygenase
ROS Kinase
Wnt/beta-catenin
Kras
CXCR
Retinoid Receptor
GSK-3
TGF-beta/Smad
Thrombin
Serine Protease
Gamma-secretase
Trk receptor
MRP
HIF
E1/E2/E3 Enzyme
CCR
IGF-1R
Reductase
TAM Receptor
ROCK
Antifolate
P2X Receptor
FAK
Integrin
Neurokinin receptor
SGLT
Amino Acids and Derivatives
S1P Receptor
Factor Xa
CFTR
Leukotriene Receptor
Guanylate cyclase
p53
PKA
NADPH
Chk
Vasopressin Receptor
Sigma receptor
Cannabinoid Receptor
DHFR
DNA Alkylation
ATM/ATR
Molecular Glues
Syk
ADC Cytotoxin
Histone Demethylase
Hydroxylase
Glutathione Peroxidase
FXR
Tyrosinase
DNA-PK
NOD-like Receptor (NLR)
BTK
OX Receptor
DNA gyrase
CSF-1R
Glucosidase
Hedgehog/Smoothened
CaMK
S6 Kinase
P2Y Receptor
RSV
Indoleamine 2,3-Dioxygenase (IDO)
Isocitrate Dehydrogenase (IDH)
NOD
IAP
ABC Transporter
Sirtuin
NOS
Xanthine Oxidase
IκB/IKK
IDO
DNA Methyltransferase
MAPK
PLK
Aminopeptidase
Chloride channel
Beta-Secretase
Complement System
Kinesin
Mdm2
Monoamine Transporter
DNA
Casein Kinase
Cysteine Protease
Aryl Hydrocarbon Receptor
Cholecystokinin Receptor
Smo
Ligand for E3 Ligase
Glucagon Receptor
RIP kinase
Fatty Acid Synthase
PAK
Aromatase
GHSR
IRAK
Tie-2
Acyltransferase
BACE
Pim
Glucokinase
GlyT
PGE Synthase
Photosensitizer
Liver X Receptor
Ephrin Receptor
Melanocortin Receptor
Gap Junction Protein
PD-1/PD-L1
PROTACs
FAAH
Melatonin Receptor
Serine/threonin kinase
Telomerase
AhR
ROR
OAT
GPCR19
IKZF
CRM1
UGT
Thrombopoietin Receptor
CaSR
CRFR
GST
Oxytocin Receptor
LTR
PERK
Imidazoline Receptor
Bradykinin Receptor
CGRP Receptor
NADPH-oxidase
IFNAR
CETP
MT Receptor
Na-K-Cl cotransporter
Lipid
ASBT
PYK2
Glutaminase
Wee1
Cuproptosis
Protease-activated Receptor
c-Myc
Vitamin
MTP
DprE1
OXPHOS
STING
Acetyl-CoA Carboxylase
FKBP
Myosin
Decarboxylase
Neprilysin
YAP
Cell wall
Annexin A
Neuropeptide Y Receptor
LPA Receptor
PDK
Immunology/Inflammation related
Somatostatin
Mucin
BCRP
Discoidin Domain Receptor (DDR)
Arginase
Rho
NAMPT
NEDD8
ATP Citrate Lyase
Monocarboxylate transporter
LDL
Epoxide Hydrolase
Free radical scavengers
TOPK
Adenosine Deaminase
Necroptosis
Stearoyl-CoA Desaturase (SCD)
transporter
Apelin receptor
MicroRNA
Galectin
Hexokinase
DUB
Neurotensin Receptor
Survivin
Aquaporin
p97
GSNOR
Na+/Ca2+ Exchanger
HCN Channel
Histone Acetyltransferase
PAI-1
VDA
NR4A
Porcupine
CD73
IRE1
KSP
Huntingtin
GluCls
Pyroptosis
MLK
Taste receptor
FLAP
Integrase
Glutathione reductase
Advanced Glycation End Products
Phosphorylase
SGK
Ligands for Target Protein for PROTAC
Lipase
PAFR
PI4K
Adenylyl Cyclase
MIF
PAD
ASK
Methionine Adenosyltransferase (MAT)
DYRK
gp120/CD4
GTPase
cAMP
MELK
Platelet aggregation
Hydrogenase
Factor VIIa
N-Acetylglucosaminyltransferase
VDAC
ATG
Adiponectin Receptor
Anion Exchanger
PROTAC Linker
glycosidase
Hippo pathway
p62
CRISPR/Cas9
RAR/RXR
MALT
Arrestin
Prolyl Endopeptidase (PREP)
MAGL
PTEN
Cadherin
RXFP receptor
PKM
NPC1L1
Kisspeptin
AAK1
SIK
Thioredoxin
FOXO
OCT
Bcl-6
Hck
Stemness kinase
Fas/FasL
GRK
AAK1 (AP2 associated kinase 1)
Arp2/3 Complex
BMI-1
Dynamin
Cell Cycle Arrest
LIM Kinase
MTH1
HCAR
MNK
KLF
Ferroportin