Drug Repurposing Compound Library

Catalog No. L9200

Library Compound List Excel SDF

Traditional de novo drug discovery and development involves an HTS campaign for de novo candidate hits and requires highly specialized screening facilities and compound libraries containing several million compounds. It is a time consuming and expensive process. As the regulation for drug safety and efficacy is increasingly getting complex, the cost of developing new drugs is keeping skyrocket. Drug repositioning, also known as old drugs for new uses, is an effective strategy to find new indications for existing drugs and has recently drawn attention and has led to several blockbuster drugs because of its high efficiency and low-cost. High-content screens, new biomarkers, noninvasive imaging techniques, and advanced in bioinformatics have created new opportunities for pursuing novel indications for approved compounds.

The Drug Repurposing Compound Library by TargetMol, containing 4330 approved and clinical drugs, which have undergone extensive preclinical studies and have well-characterized bioactivities, safety and bioavailability – properties which could dramatically accelerate drug development and optimization, is a good tool for drug repurposing and cell induction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

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If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com

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Product Description

A unique collection of 4330 approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS);
An effective tool for discovering new with old drugs, cell induction, and new drug target screening;
All approved drugs collected in this library are approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), or included in the US Pharmacopeia (USP) Dictionary, the British Pharmacopoeia (BP), the European Pharmacopoeia (EP), the Japanese Pharmacopoeia (JP), or Chinese Pharmacopoeia (CP) Dictionary;
Covers various research areas, such as cancer, cardiovascular disease, immunology, respiratory system, etc.
Covers various targets, such as 5-HT Receptor, Sodium Channel, p38 MAPK, PI3K, MEK, etc.
Detailed compound information with structure, target, activity, and brief introduction;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Library Composition

Autophagy (449)

Antibacterial (435)

Apoptosis (421)

Antibiotic (393)

Endogenous Metabolite (318)

5-HT Receptor (193)

Adrenergic Receptor (179)

AChR (153)

COX (136)

Dopamine Receptor (125)

Histamine Receptor (119)

DNA/RNA Synthesis (117)

Parasite (112)

HIV Protease (109)

Antifungal (96)

Sodium Channel (94)

Calcium Channel (86)

Potassium Channel (84)

VEGFR (78)

Topoisomerase (73)

EGFR (71)

PI3K (64)

PDE (62)

Reactive Oxygen Species (62)

P450 (58)

FLT (56)

Influenza Virus (56)

Ferroptosis (56)

GABA Receptor (54)

Estrogen/progestogen Receptor (53)

NF-κB (53)

PPAR (52)

CDK (52)

Dehydrogenase (51)

Glucocorticoid Receptor (51)

SARS-CoV (50)

HCV Protease (48)

PDGFR (48)

JAK (48)

c-Kit (46)

Microtubule Associated (46)

HDAC (45)

FGFR (43)

Prostaglandin Receptor (42)

RAAS (41)

c-Met/HGFR (40)

mTOR (39)

Mitophagy (39)

Nucleoside Antimetabolite/Analog (35)

Src (34)

Reverse Transcriptase (33)

Estrogen Receptor/ERR (32)

Serotonin Transporter (32)

HBV (32)

Virus Protease (30)

iGluR (30)

HSV (30)

Adenosine Receptor (30)

ribosome (29)

Androgen Receptor (29)

Bcr-Abl (29)

Proteasome (29)

Tyrosine Kinases (28)

Opioid Receptor (28)

AChE (27)

TNF (27)

Norepinephrine (26)

Raf (26)

MAO (25)

ATPase (25)

Progesterone Receptor (25)

GPR (25)

ROS (23)

GluR (23)

Akt (23)

NMDAR (23)

Phosphatase (23)

Proton pump (22)

Carbonic Anhydrase (22)

DNA Alkylator/Crosslinker (22)

HIF/HIF Prolyl-Hydroxylase (22)

Transferase (22)

HER (22)

Aurora Kinase (21)

PARP (21)

Epigenetic Reader Domain (21)

Beta Amyloid (21)

P-gp (21)

Antifection (21)

PKC (21)

BTK (21)

HSP (20)

MEK (20)

TRP/TRPV Channel (20)

p38 MAPK (20)

Monoamine Oxidase (19)

IL Receptor (19)

Thrombin (18)

DPP-4 (18)

ERK (18)

Antioxidant (18)

c-RET (18)

Mitochondrial Metabolism (18)

Interleukin (17)

Drug Metabolite (17)

Trk receptor (17)

Phospholipase (17)

ALK (17)

MMP (17)

AMPK (17)

CXCR (17)

BCL (16)

Retinoid Receptor (16)

E1/E2/E3 Enzyme (15)

DNA Alkylation (15)

Endothelin Receptor (15)

Thyroid hormone receptor(THR) (15)

GSK-3 (15)

c-Fms (15)

NO Synthase (15)

Caspase (15)

Antiviral (15)

Histone Methyltransferase (15)

Gamma-secretase (14)

TLR (14)

Antifolate (14)

Lipoxygenase (14)

STAT (14)

TAM Receptor (14)

MRP (14)

SGLT (13)

Syk (12)

HIF (12)

PKA (12)

CCR (12)

Chk (12)

CFTR (12)

DNA-PK (12)

HMG-CoA Reductase (12)

NADPH (12)

p53 (12)

Neurokinin receptor (11)

LPL Receptor (11)

DHFR (11)

GNRH Receptor (11)

S1P Receptor (11)

IGF-1R (11)

FAK (11)

Nrf2 (11)

Guanylate cyclase (11)

Amino Acids and Derivatives (11)

TGF-beta/Smad (10)

CaMK (10)

FXR (10)

Chloride channel (10)

ROCK (10)

Serine Protease (10)

CSF-1R (10)

DNA Methyltransferase (10)

Integrin (10)

Factor Xa (10)

Wnt/beta-catenin (10)

DNA gyrase (10)

Hedgehog/Smoothened (10)

P2X Receptor (9)

Glucosidase (9)

S6 Kinase (9)

Vasopressin Receptor (9)

Reductase (9)

Mdm2 (9)

Histone Demethylase (9)

P2Y Receptor (9)

Sigma receptor (9)

Cannabinoid Receptor (9)

Hydroxylase (9)

PLK (9)

ABC (8)

Smo (8)

Glutathione Peroxidase (8)

CAT (8)

OX Receptor (8)

IAP (8)

Tyrosinase (8)

JNK (8)

Indoleamine 2,3-Dioxygenase (IDO) (8)

CETP (8)

Leukotriene Receptor (8)

RSV (7)

Fatty Acid Synthase (7)

Aryl Hydrocarbon Receptor (7)

Ligand for E3 Ligase (7)

LTR (7)

BACE (7)

Xanthine Oxidase (7)

ROS Kinase (7)

ATM/ATR (7)

Beta-Secretase (7)

Glucagon Receptor (7)

Sirtuin (7)

Ras (7)

Monoamine Transporter (6)

PAK (6)

Aminopeptidase (6)

Complement System (6)

ROR (6)

AhR (6)

IκB/IKK (6)

Kinesin (6)

Cysteine Protease (6)

RIP kinase (6)

DNA (6)

Isocitrate Dehydrogenase (IDH) (6)

Casein Kinase (6)

FAAH (5)

Imidazoline Receptor (5)

Glucokinase (5)

Cell wall (5)

Tie-2 (5)

NOD (5)

Anti-infection (5)

Liver X Receptor (5)

IDO (5)

Acyltransferase (5)

GPCR19 (5)

PGE Synthase (5)

Ephrin Receptor (5)

Pim (5)

NOS (5)

IFNAR (5)

cholecystokinin (4)

CaSR (4)

Gap Junction Protein (4)

Melatonin Receptor (4)

CGRP Receptor (4)

Serine/threonin kinase (4)

CRFR (4)

MT Receptor (4)

Bradykinin Receptor (4)

GHSR (4)

KSP (4)

NOD-like Receptor (NLR) (4)

Acetyl-CoA Carboxylase (4)

Lipid (4)

Molecular Glues (4)

Neprilysin (4)

UGT (4)

DprE1 (4)

Decarboxylase (4)

Melanocortin Receptor (4)

GlyT (4)

Rho (3)

Aromatase (3)

Adenosine deaminase (3)

NAMPT (3)

Free radical scavengers (3)

Protease-activated Receptor (3)

Hexokinase (3)

Arginase (3)

CRM1 (3)

Monocarboxylate transporter (3)

Annexin A (3)

NADPH-oxidase (3)

IRAK (3)

Telomerase (3)

STING (3)

Oxytocin Receptor (3)

PDK (3)

LDL (3)

Neuropeptide Y Receptor (3)

OAT (3)

LPA Receptor (3)

Myosin (3)

Na-K-Cl cotransporter (3)

GST (3)

Somatostatin (3)

PD-1/PD-L1 (2)

Wee1 (2)

Taste receptor (2)

PYK2 (2)

MLK (2)

Glutathione reductase (2)

advanced glycation end products (2)

IRE1 (2)

Integrase (2)

NEDD8 (2)

DUB (2)

Porcupine (2)

PAI-1 (2)

Ligands for Target Protein for PROTAC (2)

VDA (2)

CD73 (2)

Phosphorylase (2)

PKM (2)

TOPK (2)

Thrombopoietin Receptor (2)

BCRP (2)

Discoidin Domain Receptor (DDR) (2)

YAP (2)

Aquaporin (2)

Epoxide Hydrolase (2)

Lipase (2)

ATP Citrate Lyase (2)

Histone Acetyltransferase (2)

Galectin (2)

MAPK (2)

PROTAC Linker (2)

MTH1 (1)

FLAP (1)

Methionine Adenosyltransferase (MAT) (1)

RAR/RXR (1)

GTPase (1)

c-Myc (1)

Thioredoxin (1)

Motilin Receptor (1)

Na+/Ca2+ Exchanger (1)

Adiponectin receptor (1)

MALT (1)

p97 (1)

PI4K (1)

NPC1L1 (1)

DYRK (1)

LHRH (1)

KLF (1)

Fas/FasL (1)

CRISPR/Cas9 (1)

PROTACs (1)

PERK (1)

Dynamin (1)

Glutaminase (1)

OXPHOS (1)

Hydrogenase (1)

Hippo pathway (1)

SGK (1)

MNK (1)

BMI-1 (1)

N-Acetylglucosaminyltransferase (1)

AAK1 (AP2 associated kinase 1) (1)

MELK (1)

Hck (1)

PAD (1)

GRK (1)

PAFR (1)

Stearoyl-CoA Desaturase (SCD) (1)

Pyroptosis (1)

Survivin (1)

cAMP (1)

Platelet aggregation (1)

Immunology/Inflammation related (1)

VDAC (1)

Angiotensin-converting Enzyme (ACE) (1)

GSNOR (1)

GluCls (1)

Anion Exchanger (1)

Adenylyl cyclase (1)

ACK (1)

transporter (1)

Stemness kinase (1)

ASK (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty