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Anti-PP2A alpha/beta Antibody (6N831)
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Catalog No. TMAC-03393
Alias Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Serine/threonine protein phosphatase 2A catalytic subunit beta isoform, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform, RP-C, RP C, Replication protein C, Protein phosphatase 2 catalytic subunit beta isoform, Protein phosphatase 2 catalytic subunit alpha isoform, PPP2CB, PPP2CA, PP2CB, PP2Aα/β, PP2Ac, PP2Aalpha/beta, PP2A-alpha, PP2AA_HUMAN, PP2Aa/b, PP2A α/β, PP2A beta, PP2A B, PP2A alpha, PP2A a/b, PP2A A
Anti-PP2A alpha/beta Antibody (6N831) is a Rabbit antibody targeting PP2A alpha/beta. Anti-PP2A alpha/beta Antibody (6N831) can be used in WB,ICC,IHC,IP.
Anti-PP2A alpha/beta Antibody (6N831)
Anti-PP2A alpha/beta Antibody (6N831)
😃Good
Catalog No. TMAC-03393Alias Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Serine/threonine protein phosphatase 2A catalytic subunit beta isoform, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform, RP-C, RP C, Replication protein C, Protein phosphatase 2 catalytic subunit beta isoform, Protein phosphatase 2 catalytic subunit alpha isoform, PPP2CB, PPP2CA, PP2CB, PP2Aα/β, PP2Ac, PP2Aalpha/beta, PP2A-alpha, PP2AA_HUMAN, PP2Aa/b, PP2A α/β, PP2A beta, PP2A B, PP2A alpha, PP2A a/b, PP2A A
Anti-PP2A alpha/beta Antibody (6N831) is a Rabbit antibody targeting PP2A alpha/beta. Anti-PP2A alpha/beta Antibody (6N831) can be used in WB,ICC,IHC,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-PP2A alpha/beta Antibody (6N831) is a Rabbit antibody targeting PP2A alpha/beta. Anti-PP2A alpha/beta Antibody (6N831) can be used in WB,ICC,IHC,IP. |
| Synonyms | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, Serine/threonine protein phosphatase 2A catalytic subunit beta isoform, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform, RP-C, RP C, Replication protein C, Protein phosphatase 2 catalytic subunit beta isoform, Protein phosphatase 2 catalytic subunit alpha isoform, PPP2CB, PPP2CA, PP2CB, PP2Aα/β, PP2Ac, PP2Aalpha/beta, PP2A-alpha, PP2AA_HUMAN, PP2Aa/b, PP2A α/β, PP2A beta, PP2A B, PP2A alpha, PP2A a/b, PP2A A |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat,zebrafish |
| Verified Activity | 1. Western blot analysis of PP2A alpha + beta on different lysates using anti-PP2A alpha + beta antibody at 1/1,000 dilution. Positive control: Lane 1: A431, Lane 2: NIH/3T3, Lane 3: 293T. 2. Western blot analysis of PP2A alpha + beta on hybrid fish (crucian-carp) brain tissue lysate using anti-PP2A alpha + beta antibody at 1/500 dilution. 3. Immunohistochemical analysis of paraffin-embedded mouse stomach tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PP2A alpha + beta antibody. Counter stained with hematoxylin. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:100-200; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The catalytic subunit of protein phosphatase 2A (PP2A) is inactivated by in vitro phosphorylation of Tyr-307 by receptor and nonreceptor protein tyrosine kinases. The catalytic subunit of PP2A is phosphorylated by tyrosine-specific protein kinases and associates with a variety of regulatory subunits. Phosphorylation is enhanced in the presence of the phosphatase inhibitor okadaic acid, consistent with an autodephosphorylation reaction. Phosphorylation is catalyzed by p60v-src, p56lck, epidermal growth factor receptors, and insulin receptors. Transient deactivation of PP2A might enhance transmission of cellular signals through kinase cascades within cells. In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Molecular Weight | Theoretical: 36 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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