TARC/CCL17 Protein, Human, Recombinant (His)

Name: TARC/CCL17 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-02061
Rating: 4.5 (1 reviews)

(Synonyms: TARC, SCYA17, chemokine (C-C motif) ligand 17, ABCD-2, A-152E5.3) Copy Product Info

Synonyms: TARC, SCYA17, chemokine (C-C motif) ligand 17, ABCD-2, A-152E5.3

Catalog No. TMPY-02061 Copy Product Info

TARC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 9.5 kDa and the accession number is Q92583-1.

TARC/CCL17 Protein, Human, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$73	7-10 days	7-10 days
10 µg	$118	7-10 days	7-10 days
20 µg	$196	7-10 days	7-10 days
50 µg	$443	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	TARC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 9.5 kDa and the accession number is Q92583-1.
Species	Human
Expression System	Baculovirus Insect Cells
Tag	C-His
Accession Number	Q92583-1
Construction	A DNA sequence encoding the full length of human CCL17 (Q92583-1) (Met 1-Ser 94) was expressed, fused with a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 24
Protein Purity	> 94 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM NaCl, pH 7.4, 10% gly. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	TARC, SCYA17, chemokine (C-C motif) ligand 17, ABCD-2, A-152E5.3
Research Background	Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.

Chemical Properties

Molecular Weight

9.5 kDa (predicted); 12 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.