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PFK-158

Name: PFK-158
Brand: TargetMol
SKU: T3105
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3105Cas No. 1462249-75-7

PFK-158 is an effective and specific inhibitor PFKFB3.

PFK-158

🥰Excellent

Purity: 99.16%

Catalog No. T3105Cas No. 1462249-75-7

PFK-158 is an effective and specific inhibitor PFKFB3.

Pack Size	Price	Availability
1 mg	$30	In Stock
2 mg	$40	In Stock
5 mg	$64	In Stock
10 mg	$97	In Stock
25 mg	$183	In Stock
50 mg	$287	In Stock
100 mg	$455	In Stock
1 mL x 10 mM (in DMSO)	$70	In Stock

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Batch Information

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Purity:99.16%

Resource Download

COA LCMS

Product Introduction

Bioactivity

Description	PFK-158 is an effective and specific inhibitor PFKFB3.
Targets&IC50	PFKFB3:137 nM (IC50 )

Chemical Properties

Molecular Weight	328.29
Formula	C₁₈H₁₁F₃N₂O
Cas No.	1462249-75-7
Smiles	FC(F)(F)c1ccc2ccc(\C=C\C(=O)c3ccncc3)nc2c1
Relative Density.	1.346 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (152.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0461 mL	15.2304 mL	30.4609 mL	152.3044 mL
5 mM	0.6092 mL	3.0461 mL	6.0922 mL	30.4609 mL
10 mM	0.3046 mL	1.5230 mL	3.0461 mL	15.2304 mL
20 mM	0.1523 mL	0.7615 mL	1.5230 mL	7.6152 mL
50 mM	0.0609 mL	0.3046 mL	0.6092 mL	3.0461 mL
100 mM	0.0305 mL	0.1523 mL	0.3046 mL	1.5230 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc