Shopping Cart

Your shopping cart is currently empty

Molnupiravir

Name: Molnupiravir
Brand: TargetMol
SKU: T60951
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T60951Cas No. 2492423-29-5

Alias MK-4482, Lagevrio, EIDD-2801, 2349386-89-4

Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability. Molnupiravir can be used in the study of COVID-19, seasonal and pandemic influenza, and has broad-spectrum antiviral activity against multiple coronaviruses and influenza viruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV.

Molnupiravir

Copy Product Info

😃Good

Purity: 99.98%

Catalog No. T60951Alias MK-4482, Lagevrio, EIDD-2801, 2349386-89-4Cas No. 2492423-29-5

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$34	In Stock	In Stock
10 mg	$55	In Stock	In Stock
25 mg	$72	In Stock	In Stock
50 mg	$122	In Stock	In Stock
100 mg	$197	In Stock	In Stock
200 mg	$372	In Stock	In Stock
500 mg	$788	In Stock	In Stock
1 g	$1,080	-	In Stock
1 mL x 10 mM (in DMSO)	$61	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.98%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability. Molnupiravir can be used in the study of COVID-19, seasonal and pandemic influenza, and has broad-spectrum antiviral activity against multiple coronaviruses and influenza viruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV.
In vitro	METHODS: RD, Huh7, and Vero cells were treated with Molnupiravir (MK-4482) (EIDD-2801) (1, 10, 100 μM) for cytopathic effect (CPE) protection assay. RESULTS EIDD-2801 showed stable CPE protection potential in a dose-dependent manner in multiple cell lines infected with EV-A71 virus; the value against EV-A71 virus was 70.12±4.40μM in RD cells; 88.52±3.18μM in Vero cells, and 35.64±0.47μM in Huh7 cells. [1]
In vivo	METHODS: Molnupiravir (MK-4482) (EIDD-2801) (50, 150, or 500 mg/kg, orally, every 12 hours) was used to prophylactically treat mice infected with SARS-CoV and observe its effects in mice. RESULTS Molnupiravir has potent antiviral activity and is able to prevent SARS-CoV replication and disease. [1]
Synonyms	MK-4482, Lagevrio, EIDD-2801, 2349386-89-4

Chemical Properties

Molecular Weight	329.31
Formula	C₁₃H₁₉N₃O₇
Cas No.	2492423-29-5
Smiles	CC(C)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc\c(=N/O)[nH]c1=O

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 257.5 mg/mL (781.94 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.07 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0367 mL	15.1833 mL	30.3665 mL	151.8326 mL
5 mM	0.6073 mL	3.0367 mL	6.0733 mL	30.3665 mL
10 mM	0.3037 mL	1.5183 mL	3.0367 mL	15.1833 mL
20 mM	0.1518 mL	0.7592 mL	1.5183 mL	7.5916 mL
50 mM	0.0607 mL	0.3037 mL	0.6073 mL	3.0367 mL
100 mM	0.0304 mL	0.1518 mL	0.3037 mL	1.5183 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc