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Anti-LEU5 Polyclonal Antibody
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Catalog No. TMAB-01062
Alias Tripartite motif protein 13, TRIM13, TRI13, RNF77, RING finger protein 77, Ret finger protein 2, Putative tumor suppressor RFP2, Leukemia associated protein 5, LEU5, HGNC:9976, DLEU5, CAR, B cell chronic lymphocytic leukemia tumor suppressor Leu5
Anti-LEU5 Polyclonal Antibody is a Rabbit antibody targeting LEU5. Anti-LEU5 Polyclonal Antibody can be used in WB.
Anti-LEU5 Polyclonal Antibody
Anti-LEU5 Polyclonal Antibody
😃Good
Catalog No. TMAB-01062Alias Tripartite motif protein 13, TRIM13, TRI13, RNF77, RING finger protein 77, Ret finger protein 2, Putative tumor suppressor RFP2, Leukemia associated protein 5, LEU5, HGNC:9976, DLEU5, CAR, B cell chronic lymphocytic leukemia tumor suppressor Leu5
Anti-LEU5 Polyclonal Antibody is a Rabbit antibody targeting LEU5. Anti-LEU5 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-LEU5 Polyclonal Antibody is a Rabbit antibody targeting LEU5. Anti-LEU5 Polyclonal Antibody can be used in WB. |
| Synonyms | Tripartite motif protein 13, TRIM13, TRI13, RNF77, RING finger protein 77, Ret finger protein 2, Putative tumor suppressor RFP2, Leukemia associated protein 5, LEU5, HGNC:9976, DLEU5, CAR, B cell chronic lymphocytic leukemia tumor suppressor Leu5 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Horse,Rabbit,Sheep) |
| Verified Activity | 1. Sample: Liver (Mouse) Lysate at 40 μg Primary: Anti-LEU5 (TMAB-01062) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kDa Observed band size: 48 kDa 2. Sample: Lane 1: Mouse Testis Lysates Lane 2: Rat Testis Lysates Lane 3: Rat LympHLysates Lane 4: Human HL-60 cell Lysates Lane 5: Human SH-SY5Y cell Lysates Lane 6: Human HeLa cell Lysates Primary: Anti-LEU5 (TMAB-01062) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kDa Observed band size: 47 kDa   |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Concentrates and colocalizes with p62/SQSTM1 and ZFYVE1 at the perinuclear endoplasmic reticulum. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Immunogen | KLH conjugated synthetic peptide: human LEU5/RFP2 |
| Antigen Species | Human |
| Gene Name | TRIM13 |
| Gene ID | |
| Protein Name | E3 ubiquitin-protein ligase TRIM13 |
| Uniprot ID | |
| Biology Area | Cell Cycle Inhibitors,Ubiquitin ligases,Ubiquitylation,Developmental Families,NFkB Pathway |
| Function | E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor. |
| Molecular Weight | Theoretical: 47 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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