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Anti-N Cadherin Antibody (3P729)
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Catalog No. TMAH-00250
Alias NCAD, CDw325, CDHN, CD325, cadherin 2, type 1, N-cadherin (neuronal)
Anti-N Cadherin Antibody (3P729) is an antibody targeting N Cadherin. Anti-N Cadherin Antibody (3P729) can be used in ELISA, IHC.
Anti-N Cadherin Antibody (3P729)
Anti-N Cadherin Antibody (3P729)
😃Good
Catalog No. TMAH-00250Alias NCAD, CDw325, CDHN, CD325, cadherin 2, type 1, N-cadherin (neuronal)
Anti-N Cadherin Antibody (3P729) is an antibody targeting N Cadherin. Anti-N Cadherin Antibody (3P729) can be used in ELISA, IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $348 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Monoclonal Application: ELISA, IHC Reactivity: Human |
| Alias | NCAD, CDw325, CDHN, CD325, cadherin 2, type 1, N-cadherin (neuronal) |
| Ig Type | Rabbit IgG |
| Clone | 3P729 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-00250 diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | ELISA, IHC |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Cell membrane, sarcolemma. Cell junction. Cell surface. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human N Cadherin |
| Antigen Species | Human |
| Gene ID | 1000 |
| Uniprot ID | |
| Biology Area | Cancer, Signal transduction, Stem cells |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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