GAPDH Protein, Human, Recombinant (His)

Name: GAPDH Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-02446
Rating: 4.5 (1 reviews)

(Synonyms: HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase, GAPD, G3PD) Copy Product Info

Synonyms: HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase, GAPD, G3PD

Catalog No. TMPY-02446 Copy Product Info

GAPDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 38 kDa and the accession number is P04406.

Pack Size	Price	USA Stock	Global Stock
10 µg	$253	7-10 days	7-10 days
20 µg	$380	7-10 days	7-10 days
50 µg	$645	7-10 days	7-10 days
100 µg	$968	7-10 days	7-10 days
200 µg	$1,450	7-10 days	7-10 days
500 µg	Inquiry	7-10 days	7-10 days
1 mg	Inquiry	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its ability to catalyze D-glyceraldehyde 3-phosphate to 3-phosphoglycerate , the specific activity is >2500pmols/min/ug.
Description	GAPDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 38 kDa and the accession number is P04406.
Species	Human
Expression System	E. coli
Tag	N-His
Accession Number	P04406
Construction	A DNA sequence encoding the human GAPDH (P04406) (Met 1-Glu 335) was expressed, with a polyhistidine tag at the N-terminus. Predicted N terminal: Met
Protein Purity	> 93 % as determined by SDS-PAGE
Endotoxin	Please contact us for more information.
Formulation	Supplied as sterile 50 mM Tris, 30% glycerol, pH 7.5.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase, GAPD, G3PD
Research Background	Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions.

Chemical Properties

Molecular Weight

38 kDa (predicted); 38 kDa (reducing conditions)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.