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Polygalacturonic acid
🥰Excellent
Catalog No. T78490Cas No. 25990-10-7
Alias Galacturonic acid polymer
Polygalacturonic acid (Galacturonic acid polymer) is a transparent, gel-like polymer that constitutes a key component of the plant cell wall, and Polygalacturonic acid has been applied in the synthesis of silver nanoparticles (AgNPs), acting as an antioxidant and anti-inflammatory agent to protect cells from ROS-induced damage and promote wound healing, while Polygalacturonic acid nanoparticles additionally exhibit antimicrobial properties, providing multifunctional applications in biomedical research and nanomaterial development.
Polygalacturonic acid
Polygalacturonic acid
🥰Excellent
Catalog No. T78490Alias Galacturonic acid polymerCas No. 25990-10-7
Polygalacturonic acid (Galacturonic acid polymer) is a transparent, gel-like polymer that constitutes a key component of the plant cell wall, and Polygalacturonic acid has been applied in the synthesis of silver nanoparticles (AgNPs), acting as an antioxidant and anti-inflammatory agent to protect cells from ROS-induced damage and promote wound healing, while Polygalacturonic acid nanoparticles additionally exhibit antimicrobial properties, providing multifunctional applications in biomedical research and nanomaterial development.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 500 mg | $30 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Chemical Properties
| Description | Polygalacturonic acid (Galacturonic acid polymer) is a transparent, gel-like polymer that constitutes a key component of the plant cell wall, and Polygalacturonic acid has been applied in the synthesis of silver nanoparticles (AgNPs), acting as an antioxidant and anti-inflammatory agent to protect cells from ROS-induced damage and promote wound healing, while Polygalacturonic acid nanoparticles additionally exhibit antimicrobial properties, providing multifunctional applications in biomedical research and nanomaterial development. |
| In vitro | The Polygalacturonic acid-hyaluronate composite hydrogel conjugated with Ibuprofen can effectively prevent epidural fibrosis (a severe adhesive scar tissue disorder) in adult male rats after laminectomy, while improving local inflammatory control efficiency and reducing the side effects of Ibuprofen [1]. The Polygalacturonic acid-hyaluronate composite hydrogel (PGA-HA, concentration 2%, volume 200 μL) exhibited only low cytotoxicity against mouse fibroblast L929 cells after 24 hours of treatment [1]. |
| In vivo | In the regulation of immune function and intestinal microbiota in mice with ulcerative colitis (UC), oral administration of Polygalacturonic acid showed more pronounced effects on intestinal mucosal lamina propria immunity and gut microbiota modulation, while intravenous injection of Polygalacturonic acid demonstrated superior benefits in splenic immune regulation [2]. |
| Synonyms | Galacturonic acid polymer |
| Formula | (C6H10O7)x |
| Cas No. | 25990-10-7 |
| Color | Yellow |
| Appearance | Solid |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: < 1 mg/mL (insoluble) 0.1 M NaOH: 8 mg/mL, when pH is adjusted to 11 with NaOH. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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