Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Polygalacturonic acid (Galacturonic acid polymer), a transparent colloid, constitutes a significant portion of the cell wall. It is employed in the synthesis of silver nanoparticles (AgNPs), serving both as an antioxidant and anti-inflammatory agent to shield cells from the harmful impacts of elevated reactive oxygen species (ROS) and to expedite wound healing. Additionally, Polygalacturonic acid nanoparticles exhibit antibacterial properties [1] [2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | Inquiry | $ 30.00 |
Description | Polygalacturonic acid (Galacturonic acid polymer), a transparent colloid, constitutes a significant portion of the cell wall. It is employed in the synthesis of silver nanoparticles (AgNPs), serving both as an antioxidant and anti-inflammatory agent to shield cells from the harmful impacts of elevated reactive oxygen species (ROS) and to expedite wound healing. Additionally, Polygalacturonic acid nanoparticles exhibit antibacterial properties [1] [2]. |
In vitro | Polygalacturonic acid forms a robust hydrogel that extends drug efficacy. For instance, a conjugate of polygalacturonic acid hydrogel/hyaluronate with ibuprofen mitigates epidural fibrosis in laminectomized male adult rats, enhances localized inflammation management, and diminishes ibuprofen's side effects [1]. Furthermore, at a concentration of 2% in 200 μL applied over 24 hours, the polygalacturonic acid hydrogel/hyaluronate (PGA-HA) demonstrates minimal cytotoxicity in L929 fibroblasts [1]. Additionally, nanoparticles formulated from polygalacturonic acid (PGA) combined with silver and hyaluronate (Ag-PGA/HA) within a polyvinyl alcohol (PVA) matrix exhibit antibacterial properties against both gram-positive bacteria—Bacillus subtilis and Staphylococcus aureus—and the gram-negative bacterium Escherichia coli [2]. |
In vivo | Polygalacturonic acid, when applied externally for 14 days, accelerates wound healing in albino rats with infections [2]. |
Synonyms | Galacturonic acid polymer |
Molecular Weight | N/A |
Formula | (C6H10O7)x |
CAS No. | 25990-10-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Polygalacturonic acid 25990-10-7 Galacturonic acid polymer inhibitor inhibit