Shopping Cart

Your shopping cart is currently empty

Polygalacturonic acid

Name: Polygalacturonic acid
Brand: TargetMol
SKU: T78490
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T78490Cas No. 25990-10-7

Alias Galacturonic acid polymer

Polygalacturonic acid (Galacturonic acid polymer) is a transparent, gel-like polymer that constitutes a key component of the plant cell wall, and Polygalacturonic acid has been applied in the synthesis of silver nanoparticles (AgNPs), acting as an antioxidant and anti-inflammatory agent to protect cells from ROS-induced damage and promote wound healing, while Polygalacturonic acid nanoparticles additionally exhibit antimicrobial properties, providing multifunctional applications in biomedical research and nanomaterial development.

Polygalacturonic acid

Copy Product Info

😃Good

Catalog No. T78490Alias Galacturonic acid polymerCas No. 25990-10-7

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Appearance:Solid

Color:Yellow

Resource Download

COA

Product Introduction

Bioactivity

Description	Polygalacturonic acid (Galacturonic acid polymer) is a transparent, gel-like polymer that constitutes a key component of the plant cell wall, and Polygalacturonic acid has been applied in the synthesis of silver nanoparticles (AgNPs), acting as an antioxidant and anti-inflammatory agent to protect cells from ROS-induced damage and promote wound healing, while Polygalacturonic acid nanoparticles additionally exhibit antimicrobial properties, providing multifunctional applications in biomedical research and nanomaterial development.
In vitro	The Polygalacturonic acid-hyaluronate composite hydrogel conjugated with Ibuprofen can effectively prevent epidural fibrosis (a severe adhesive scar tissue disorder) in adult male rats after laminectomy, while improving local inflammatory control efficiency and reducing the side effects of Ibuprofen [1]. The Polygalacturonic acid-hyaluronate composite hydrogel (PGA-HA, concentration 2%, volume 200 μL) exhibited only low cytotoxicity against mouse fibroblast L929 cells after 24 hours of treatment [1].
In vivo	In the regulation of immune function and intestinal microbiota in mice with ulcerative colitis (UC), oral administration of Polygalacturonic acid showed more pronounced effects on intestinal mucosal lamina propria immunity and gut microbiota modulation, while intravenous injection of Polygalacturonic acid demonstrated superior benefits in splenic immune regulation [2].
Synonyms	Galacturonic acid polymer

Chemical Properties

Molecular Weight	194.139
Formula	(C₆H₁₀O₇)x
Cas No.	25990-10-7
Smiles	OC1O[C@@H]([C@H](O)[C@H](O)[C@H]1O)C(O)=O

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 1 mg/mL (insoluble)

0.1 M NaOH: 8.00 mg/mL (41.21 mM), when pH is adjusted to 11 with NaOH.

Solution Preparation Table

0.1 M NaOH

	1mg	5mg	10mg	50mg
1 mM	5.1509 mL	25.7547 mL	51.5095 mL	257.5474 mL
5 mM	1.0302 mL	5.1509 mL	10.3019 mL	51.5095 mL
10 mM	0.5151 mL	2.5755 mL	5.1509 mL	25.7547 mL
20 mM	0.2575 mL	1.2877 mL	2.5755 mL	12.8774 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc